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Dietary tea tree (Melaleucae Aetheroleum) oil fortifies growth, biochemical, immune-antioxidant trait, gene function, tissue reaction, and Aeromonas sobria resistance in Nile tilapia (Oreochromis niloticus).
BMC Vet Res
January 2025
Department of Biochemistry and Molecular Biology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt.
The current study had aimed to assess the long-term dietary supplementation with Melaleucae aetheroleum, tea tree essential oil (TTO). The impact on growth performance, biochemical indices, immune function, oxidant/antioxidant activity, gene expression, histopathology, and resistance against Aeromonas sobria in Nile tilapia (Oreochromis niloticus) was investigated. Four groups (with five replicates; G1 (control group, G2, G3, and G4) of Nile tilapia received diets enriched with TTO (doses of 0.
View Article and Find Full Text PDFReprogramming macrophages to treat liver diseases.
Hepatology
November 2024
Department of Biomedicine, School of Medicine, University of Barcelona, Barcelona, Spain.
Cutting-edge research has expanded our understanding of the macrophage activation programs in liver diseases making this immune cell type a therapeutic target. Clinical data on macrophage infiltration and polarization states have been used to help predict mortality or poor prognosis in patients with liver cirrhosis and/or HCC. The latest single-cell and spatial transcriptomics studies have dissected unforeseen aspects depicting the immense heterogeneity of macrophages and their multifaceted role in both promoting and resolving hepatic inflammation, injury, and fibrosis.
View Article and Find Full Text PDFAdvanced strategies for intensive care management of acute liver failure.
Best Pract Res Clin Gastroenterol
December 2024
Department of Anesthesiology and Critical Care, Hospital of the University of Pennsylvania, Philadelphia, PA, 19104, USA.
Acute liver failure (ALF) is defined as the loss of hepatic function in conjunction with hepatic encephalopathy and coagulopathy. There is histological evidence of profound hepatocyte damage. If it is not aggressively managed, ALF can be fatal within a few days.
View Article and Find Full Text PDFFeasibility, classification and potential clinical impact of non-invasive delineation of abdominal lymphatic vessels in patients following TCPC with T2 weighted MRI.
Sci Rep
November 2024
Department of Pediatric Cardiology, University Children's Hospital, University of Tübingen, Tübingen, Germany.
Recent research in patients with functionally univentricular hearts (UVH) is focusing on pathologies of the lymphatic vessels. Morphology of the abdominal lymphatic vessels was analyzed by MRI in patients with UVH following total cavopulmonary connection (TCPC) and it was examined, if clinical and laboratory parameters correlate with changes after TCPC. We prospectively examined 33 patients at the age of 19.
View Article and Find Full Text PDFNON-INVASIVE METHOD OF MONITORING INTRACRANIAL PRESSURE FOR THE EVALUATION OF HEPATIC ENCEPHALOPATHY.
Arq Gastroenterol
November 2024
Faculdade de Medicina de São José do Rio Preto, Departamento de Cardiologia e Cirurgia Cardiovascular, São José do Rio Preto, São Paulo , Brasil.
Article Synopsis
- The study investigates a new non-invasive method for monitoring intracranial pressure (ICP) in patients with liver diseases and hepatic encephalopathy (HE), aiming to provide an alternative to invasive techniques.
- It uses a specific equipment, Brain4Care® BWS, to analyze ICP pulse morphology and correlates it with clinical signs of HE, focusing on key peaks that indicate intracranial compliance.
- Results show significant differences in ICP patterns between patients with and without HE, highlighting the method's potential for effective monitoring and assessment in clinical settings.
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