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A Chemometric-Assisted Colorimetric-Based Inexpensive Paper Biosensor for Glucose Detection.
Biosensors (Basel)
November 2022
Department of Mechanical Engineering, Indian Institute of Technology, Jodhpur 342037, India.
This article reports a simple and inexpensive leak-proof paper pad with an initial selection of a paper substrate on the grounds of surface morphology and fluid absorption time. Herein, a drying method is used for glucose detection on a paper pad through colorimetric analysis, and the spot detection of glucose is analyzed by optimizing the HRP concentration and volume to obtain accurate results. The rapid colorimetric method for the detection of glucose on the paper pad was developed with a limit of detection (LOD) of 2.
View Article and Find Full Text PDFDirect Interaction between -Acetylcysteine and Cytotoxic Electrophile-An Overlooked In Vitro Mechanism of Protection.
Antioxidants (Basel)
July 2022
Department of Anatomy, Faculty of Medicine and Dentistry, Palacky University Olomouc, Hnevotinska 3, 77515 Olomouc, Czech Republic.
In laboratory experiments, many electrophilic cytotoxic agents induce cell death accompanied by reactive oxygen species (ROS) production and/or by glutathione (GSH) depletion. Not surprisingly, millimolar concentrations of -acetylcysteine (NAC), which is used as a universal ROS scavenger and precursor of GSH biosynthesis, inhibit ROS production, restore GSH levels, and prevent cell death. The protective effect of NAC is generally used as corroborative evidence that cell death induced by a studied cytotoxic agent is mediated by an oxidative stress-related mechanism.
View Article and Find Full Text PDFApropos: 'Preliminary evaluation on the efficiency of the kit Platelia Dengue NS1 Ag-ELISA to detect dengue virus in dried Aedes aegypti: a potential tool to improve dengue surveillance'.
Parasit Vectors
April 2014
Sant Parmanand Hospital, 18 Alipore Road, Delhi 110054, India.
Only simple, point-of-care, assay formats of the Platellia Dengue NS1 Ag-ELISA would be suitable to identify Dengue virus in Aedes aegypti mosquitoes in dengue-endemic areas lacking sophisticated laboratory infrastructure and trained laboratory personnel.
View Article and Find Full Text PDFUnderstanding anomalous delays in a model of intracellular calcium dynamics.
Chaos
December 2010
Department of Mathematics, University of Auckland, Private Bag, 92019 Auckland, New Zealand.
In many cell types, oscillations in the concentration of free intracellular calcium ions are used to control a variety of cellular functions. It has been suggested [J. Sneyd et al.
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