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Evaluating Brain Activity in Patients With Chronic Disorders of Consciousness After Traumatic Brain Injury Using EEG Microstate Analysis During Hyperbaric Oxygen Therapy.
CNS Neurosci Ther
January 2025
Department of Hyperbaric Oxygenation, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Background: Hyperbaric oxygen (HBO) therapy is an efficacious intervention for patients with prolonged disorders of consciousness (pDOC). Electroencephalographic (EEG) microstate analysis can provide an assessment of the global state of the brain. Currently, the misdiagnosis rate of consciousness-level assessments in patients with pDOC is high.
View Article and Find Full Text PDFAssociation between anti-seizure medications and cardiac arrhythmias in patients undergoing ambulatory electroencephalographic and electrocardiographic monitoring.
Seizure
January 2025
Faculty of Medicine, Dentistry & Health Sciences, The University of Melbourne, 29 Regent Street, Fitzroy VIC 3065, Australia; Seer Medical, Melbourne, Victoria, Australia; Department of Neurology, St Vincent's Hospital Melbourne, 41 Victoria Parade Fitzroy VIC 3065, Australia.
Background Anti-seizure medications (ASMs) are commonly prescribed in epilepsy. However some have been associated with adverse cardiac outcomes including cardiac arrhythmias. Methods We conducted an observational study evaluating patients aged ≥16 years undergoing ambulatory video - electroencephalographic (EEG) - electrocardiographic (ECG) monitoring (AVEEM) between 2020 and 2023 in Australia.
View Article and Find Full Text PDFImproving and decentralising neuropaediatric healthcare in Nicaragua by implementing an education programme. A pre-experimental study.
Enferm Clin (Engl Ed)
January 2025
Departamento de Enfermería, Facultad de Enfermería, Fisioterapia y Podología, Universidad de Sevilla, Grupo de Investigación PAIDI CTS1050: «Cuidados Complejos, Cronicidad y Resultados en Salud», Sevilla, Spain. Electronic address:
Objective: To improve and decentralize neuropediatric healthcare in Nicaragua by implementing an education program.
Method: This study is carried out as an international cooperation proyecto between September 2018 and June 2019. It has a pre-experimental and before-after design (on a single group) of the implementation of an education program.
Electroencephalographic (EEG) recordings in individuals with Fragile X Syndrome (FXS) and the mouse model of FXS ( KO) display cortical hyperexcitability at rest, as well as deficits in sensory-driven cortical network synchrony. A form of circuit hyperexcitability is observed in cortical slices of KO mice as prolonged persistent activity, or Up, states. It is unknown if the circuit mechanisms that cause prolonged Up states contribute to FXS-relevant EEG phenotypes.
View Article and Find Full Text PDFNoradrenergic suppression to reduce electroencephalographic arousal after intubation: a randomised, placebo-controlled trial.
BJA Open
March 2025
Department of Anaesthetics, Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Background: Intraoperative awareness, without explicit recall, occurs after induction of anaesthesia in approximately 10% of persons under 40 yr of age. Most anaesthetic agents minimally suppress the noradrenergic system. We hypothesised that addition of dexmedetomidine, which suppresses noradrenergic activity, may reduce encephalographic (EEG) arousal in response to tracheal intubation; such an effect would lay the foundation for future studies of dexmedetomidine in reducing intraoperative awareness.
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