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Lasers Med Sci
January 2025
Laboratory of Pathophysiology Experimental, Postgraduate Program in Health Sciences, Universidade do Extremo Sul Catarinense (UNESC), Criciúma, SC, Brazil.
Unlabelled: This study aimed to evaluate gold nanoparticles (GNPs) and photobiomodulation (PBM), associated with antibothropic serum (AS), to treat a muscle lesion induced by Bothrops jararaca venom.
Methods: 108 Swiss male mice were used, divided into nine groups (n = 12) with different combinations of treatments. Animals were inoculated with 250 µg of B.
Angew Chem Int Ed Engl
January 2025
University Pardubice Faculty of Chemical Technology: Univerzita Pardubice Fakulta Chemicko-Technologicka, Department of General and Inorganic Chemistry, CZECHIA.
Wade's rules are a well-established tool for the description of the geometry of inorganic clusters. Among others, they state that a decrease or increase in charge is always accompanied by a change in the number of skeletal electron pairs (SEPs). This work reports the synthesis of the first cationic chalcogenaboranes closo-[12-X-2-IPr-1-EB11H10]BF4 (X = H, I; E = S, Se 3a/b, 4a/b) featuring the same SEP count as their neutral precursors, EB11H11, but bearing a positive charge.
View Article and Find Full Text PDFJDS Commun
January 2025
Department of Animal Sciences, Purdue University, West Lafayette, IN 47907.
Periparturient dairy cows experience metabolic adaptations to prepare for increased nutrient requirements of the fetus and the onset of lactation. Adaptations include increased peripheral tissue insulin resistance, which can be evaluated experimentally using intravenous glucose tolerance tests (IVGTT). The objective of this study was to determine if prepartum skeletal muscle reserves and supplementation of branched-chain volatile fatty acids (BCVFA) in the prepartum period affected blood glucose, β-hydroxybutyrate (BHB), and insulin concentrations 2 wk prepartum and 1 wk postpartum utilizing an IVGTT.
View Article and Find Full Text PDFJ Venom Anim Toxins Incl Trop Dis
January 2025
Department of Biochemistry, School of Medicine, University of Costa Rica, San José, Costa Rica.
Background: Fish venoms have been poorly characterized and the available information about their composition suggests they are uncomplicated secretions that, combined with epidermal mucus, could induce an inflammatory reaction, excruciating pain, and, in some cases, local tissue injuries.
Methods: In this study, we characterized the 24-hour histopathological effects of lionfish venom in a mouse experimental model by testing the main fractions obtained by size exclusion-HPLC. By partial proteomics analysis, we also correlated these effects with the presence of some potentially toxic venom components.
Carbon-carbon (C/C) composites are attractive materials for high-speed flights and terrestrial atmospheric reentry applications due to their insulating thermal properties, thermal resistance, and high strength-to-weight ratio. It is important to understand the evolving structure-property correlations in these materials during pyrolysis, but the extreme laboratory conditions required to produce C/C composites make it difficult to quantify the properties . This work presents an atomistic modeling methodology to pyrolyze a crosslinked phenolic resin network and track the evolving thermomechanical properties of the skeletal matrix during simulated pyrolysis.
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