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Genetics of Tourette Syndrome.
Psychiatr Clin North Am
March 2025
Department of Psychiatry and Yale Child Study Center, Yale School of Medicine, 230 South Frontage Road, New Haven, CT 06520, USA. Electronic address:
This review explores the genetic basis of Tourette syndrome (TS), a complex neuropsychiatric disorder characterized by motor and vocal tics. Family, twin, and molecular genetic studies provide strong evidence for a genetic component in TS, with heritability estimates ranging from 50% to 80%. The genetic architecture of TS is complex, involving both common variants with small effects and rare variants with larger effects.
View Article and Find Full Text PDFGenetic and nongenetic variation of multiple births in Austrian dual-purpose cows.
JDS Commun
January 2025
Department of Agronomy, Food, Natural Resources, Animals and Environment, University of Padova, 35020 Legnaro (PD), Italy.
In recent decades, a general increase in multiple birth (MB) rate has been reported in both dairy and dual-purpose cattle breeds. As there is evidence that MB has negative effects on economically important traits in dairy cows, the aims of this study were to (i) investigate environmental and genetic factors affecting MB rate and (ii) assess the impact of MB on productive and nonproductive traits of the Austrian dual-purpose breeds Pinzgauer and Tyrol Grey. The dataset included 99,141 calvings of 33,791 Pinzgauer and 68,454 calvings of 19,244 Tyrol Grey cows recorded from 2000 to 2022.
View Article and Find Full Text PDFGenetic analysis of growth traits in Salem Black goats under farm conditions.
Trop Anim Health Prod
January 2025
Livestock Farm Complex, Veterinary College and Research Institute, TANUVAS, Salem, 636 001, India.
In this study, data on pedigree, production traits for 19 years (2002-2022) of Salem Black goat from the Mecheri Sheep Research Station, Tamil Nadu, India was used. Various growth traits viz., birth weight (BW), weaning weight (WW), 6-month weight (6W), 9-month weight (9W), 12-month weight (YW), pre- and post-weaning average daily gain (ADG) (3-6, 6-9, 9-12 and 3-12 months) were analyzed.
View Article and Find Full Text PDFPerformance of weighted genomic BLUP and Bayesian methods for Hanwoo carcass traits.
Trop Anim Health Prod
January 2025
Department of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk, 38541, Republic of Korea.
To improve the quality and yield of the Korean beef industry, selection criteria often focus on estimated breeding values for carcass weight (CWT), eye muscle area (EMA), backfat thickness (BF), and marbling score (MS). This study estimated genetic parameters and assessed the accuracy of genomic estimated breeding values (GEBVs) using SNP weighting methods. We compared the accuracy of these methods with the genomic best linear unbiased prediction (GBLUP) and various Bayesian approaches (BayesA, BayesB, BayesC, and BayesCPi) for the specified traits.
View Article and Find Full Text PDFFade into you: genetic control of pigmentation patterns in red-flesh apple ().
Front Plant Sci
January 2025
Univ Angers, Institut Agro, INRAE, IRHS, SFR QUASAV, Angers, France.
The genetic basis of type 1 red-flesh color development in apple () depends upon a particular allele of the gene. Interestingly, type 1 red-flesh apples are fully red after fruit set, but anthocyanin pigmentation in apple fruit cortex may decrease during fruit growth and maturation, leading to variable red patterning and intensities in the mature cortical flesh. We developed a histogram-based color analysis method to quantitatively estimate pigmentation patterns.
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