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A magnetic nano-composite coagulant has been designed, originally applied in a specific industrial waste-water treatment, and statistically investigated using Central Composite Design (CCD). The generated polynomial models were utilized to achieve a comprehensive understanding of the impact of each ingredient of PolyAluminum Chloride (PAC), PolyAcrylAmide (PAM), and Iron (III) oxide magnetic nano particles (MNP) regarding optimum limits and conditions. The concentration of each of those components has been considered as the main effective factors, which are found to be significantly correlated, affecting the Total Dissolved Solid (TDS) removal (%), the Total Suspended Solid (TSS) removal (%), and the Turbidity Reduction Rate (TRR) NTU/min.

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Advances in Functional Nucleic Acid SERS Sensing Strategies.

ACS Sens

January 2025

Center for Biomedical-photonics and Molecular Imaging, Advanced Diagnostic-Therapy Technology and Equipment Key Laboratory of Higher Education Institutions in Shaanxi Province, School of Life Science and Technology, Xidian University, Xi'an, Shaanxi 710126, China.

Functional nucleic acids constitute a distinct category of nucleic acids that diverge from conventional nucleic acid amplification methodologies. They are capable of forming intricate hybrid structures through Hoogsteen and reverse Hoogsteen hydrogen bonding interactions between double-stranded and single-stranded DNA, thereby broadening the spectrum of DNA interactions. In recent years, functional DNA/RNA-based surface-enhanced Raman spectroscopy (SERS) has emerged as a potent platform capable of ultrasensitive and multiplexed detection of a variety of analytes of interest.

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Virtual On-Call: Use of Low-Fidelity Simulation to Improve Preparedness for Practice.

Cureus

November 2024

Medical Education and Simulation, Maidstone and Tunbridge Wells National Health Service (NHS) Trust, Kent, GBR.

Background Many newly qualified doctors feel unprepared for clinical practice. The literature identifies themes including difficulties with clinical reasoning, emergency management, handover, and prioritization of tasks. Although there is an expected level of anxiety for newly qualified doctors, this appears to be amplified with respect to the first on-call shifts that encompass these themes.

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Objective: Measurement-based care (MBC) is an emerging, objective, and systematic evidence-based practice for monitoring symptom severity and treatment efficacy to assist clinicians in developing individualized treatment strategies for patients with major depressive disorder (MDD). This study aimed to identify the barriers and facilitators of enhanced MBC (eMBC) in the outpatient setting to clarify the eMBC utilization dilemma.

Methods: Between September 2022 and June 2023, we collected the opinions of healthcare providers, adult and adolescent patients, and family members of adolescent patients via online surveys.

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Beyond conventional structures: emerging complex metal oxides for efficient oxygen and hydrogen electrocatalysis.

Chem Soc Rev

December 2024

Institute for Frontier Science, Key Laboratory for Intelligent Nano Materials and Devices of the Ministry of Education, State Key Laboratory of Mechanics and Control of Mechanical Structures, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China.

The core of clean energy technologies such as fuel cells, water electrolyzers, and metal-air batteries depends on a series of oxygen and hydrogen-based electrocatalysis reactions, including the oxygen reduction reaction (ORR), oxygen evolution reaction (OER) and hydrogen evolution reaction (HER), which necessitate cost-effective electrocatalysts to improve their energy efficiency. In the recent decade, complex metal oxides (beyond simple transition metal oxides, spinel oxides and ABO perovskite oxides) have emerged as promising candidate materials with unexpected electrocatalytic activities for oxygen and hydrogen electrocatalysis owing to their special crystal structures and unique physicochemical properties. In this review, the current progress in complex metal oxides for ORR, OER, and HER electrocatalysis is comprehensively presented.

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