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Double-blind randomised trial of saline solution for gargling and nasal rinsing in SARS-CoV-2 infection.

J Glob Health

December 2024

Department of Anesthesiology, Critical Care and Pain Medicine, UTHealth, Houston, Texas, USA.

Background: Previous studies have shown that hypertonic saline nasal irrigation and gargling reduced the duration of symptoms in upper respiratory infections caused by coronavirus. This study aims to investigate the effects of two saline regimens on symptoms associated with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

Methods: Between 2020 and 2022, individuals aged 18-65 years who tested positive for SARS-CoV-2 infection via polymerase chain reaction (PCR) were randomly assigned to either low- or high-saline regimens for 14 days.

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Ventricular tachycardia (VT) is a life-threatening arrhythmia often leading to sudden cardiac death, particularly in critically ill patients. Refractory VT, characterized by recurrent episodes requiring intervention, poses unique challenges for management, necessitating advanced diagnostic and therapeutic strategies. This systematic review evaluates the impact of imaging and pharmacological treatments in managing refractory VT in critically ill patients.

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Purpose This study evaluated the efficacy of oral melatonin therapy for visual acuity and retinal and choroidal structures in patients with chronic central serous chorioretinopathy (CSCR). Methods Fourteen patients with CSCR were included; eight received oral melatonin (3 mg nightly), and six formed the control group. Best-corrected visual acuity (BCVA), central macular thickness (CMT), central choroidal thickness (CCT), and choroidal vascularity index (CVI) were assessed at baseline and after one month.

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Background The escalating global obesity epidemic requires comprehensive investigations for effective weight management strategies. Understanding the patterns, barriers, and facilitators of dietary interventions is crucial for developing effective weight management protocols. This research aims to assess dietary modification interventions among weight loss subjects in Tamilnadu, South India.

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This narrative review synthesizes evidence on the impact of sleep on athletic performance, the prevalence and causes of sleep disturbances, and effective monitoring and intervention strategies to enhance sleep quality and duration. A comprehensive review of case studies, observational studies, randomized controlled trials, systematic reviews, and meta-analyses was conducted using PubMed, Cochrane Library, and Google Scholar up to July 2024. Sleep plays a crucial role in the overall well-being and performance of athletes, yet sleep issues are highly prevalent due to factors such as competition schedules, psychological stress, and travel across time zones.

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