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Case Summary: A 12-year-old castrated male domestic shorthair cat was referred for investigation of lethargy, hindlimb weakness with plantigrade stance and ventroflexion of the neck. The cat was fed a balanced diet and had received methylprednisolone acetate at a dose of 20 mg intramuscularly every 6 months for 6 years. On blood work, severe hypokalaemia and marked elevation of muscle enzymes were noticeable.

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  • Volkmann's ischaemic contracture (VIC) is a serious condition caused by reduced blood supply to limbs, but its incidence has decreased in developed countries, though it's still common in Nepal, prompting a detailed study.
  • Over six years, 47 cases of VIC were analyzed, revealing that the majority involved preventable causes, such as tight casts and bandages, with most cases originating from province 6.
  • The study concluded that VIC is largely preventable, and 97.87% of the cases could have been avoided with proper treatment, highlighting the need for improved primary care in Nepal, particularly in provinces 6 and 3.
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Electrophysiological abnormalities of the neuromuscular transmission in two patients with botulism-like syndrome following Botulinum-A muscle injections.

Neurophysiol Clin

July 2024

Service d'ENMG et de Pathologies Neuromusculaires, Centre de Référence des Maladies Neuromusculaires PACA-Réunion-Rhône-Alpes, Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Groupement Est, 69500, Bron, France; Pathophysiology and Genetics of Neuron and Muscle, CNRS UMR 5261, INSERM U1315, Université Lyon 1, Faculté de Médecine Lyon Est, 69008, Lyon, France. Electronic address:

Botulinum neurotoxin serotype A (BoNT-A) has several therapeutic indications such as spasticity and dystonia. Although its use is generally considered safe, a systemic diffusion can lead to systemic complications, and a botulism-like syndrome can occur after intramuscular injections. Herein, two adult cases who developed general muscle weakness after a BoNT-A intramuscular injection are reported.

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  • Bladder neck stricture (BNS) is a challenging condition often seen post-trauma or prostate surgery, and current surgical techniques lack lasting success, prompting the need for innovative approaches.* -
  • The study tested a new surgical method involving Holmium laser incisions combined with a triamcinolone injection, finding that 53.3% of patients needed follow-up procedures but reported a low failure rate of 8.9% after 18 months.* -
  • Results indicate that this technique leads to satisfactory outcomes, especially for first-time BNS patients, though further research with larger groups and extended follow-up is needed to confirm findings.*
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