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A smart and environmentally friendly pesticide system was developed that could respond to environmental stimuli while mitigating environmental risks. In this study, thiabendazole (Thi), an effective fungicide, was loaded onto zeolitic imidazolate framework-8 (ZIF-8) using the impregnation method to fabricate a pH-responsive nano hybrid delivery system (Thi@ZIF-8). The results demonstrated that Thi@ZIF-8 had a rhombic dodecahedral morphology and a loading capacity of approximately 25%.

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Article Synopsis
  • Cutaneous larva migrans (CLM), also known as creeping eruption, is an infection caused by hookworms that affects the skin, particularly on the lower legs.
  • *It presents with unique red, winding lesions that appear elevated, primarily diagnosed through clinical observation.
  • *Treatment often includes topical and oral medications like ivermectin, albendazole, and thiabendazole cream.
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O-nitrobenzyl Caged Molecule Enables Photo-controlled Release of Thiabendazole.

Chembiochem

April 2024

Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai, 200237, China.

Pesticides are essential in agricultural development. Controlled-release pesticides have attracted great attentions. Base on a principle of spatiotemporal selectivity, we extended the photoremovable protective group (PRPG) into agrochemical agents to achieve controllable release of active ingredients.

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Bioactive compounds from the parasitic plant Arceuthobium vaginatum inhibit Haemonchus contortus egg hatching.

Rev Bras Parasitol Vet

December 2023

Centro Nacional de Investigación Disciplinaria en Salud Animal e Inocuidad - CENID SAI-INIFAP, Jiutepec, Morelos, México.

The aim of this study was to assess the in vitro ovicidal activity of an ethyl acetate extract from Arceuthobium vaginatum (EtOAc-E) and their subfractions (AvR5-AvR14) against Haemonchus contortus using the egg hatching inhibition (EHI) test. The EtOAc-E and subfractions were tested at 0.12-2.

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Pesticide residues have long been a major concern for food safety. In this study, a dialdehyde starch-encapsulated silver nanoparticles composite with controlled-release "hotspots" was developed as a surface-enhanced Raman scattering (SERS) substrate. At room temperature, most of the Ag NPs were encapsulated in dialdehyde starch, which is beneficial for improving stability, and when heated to the gelatinization point, Ag NPs are completely released and abundant hot spots are formed.

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