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Pulmonary Intravascular Large B-cell Lymphoma in a Patient Administered Methotrexate for Rheumatoid Arthritis.
Intern Med
February 2020
Department of Respiratory Medicine, Tokyo Dental College Ichikawa General Hospital, Japan.
A 70-year-old woman with rheumatoid arthritis undergoing methotrexate (MTX) treatment presented with dyspnea and a subfever. Computed tomography (CT) revealed a diffuse minimal ground-glass appearance in both lungs and splenomegaly. The gallium scintigram showed a diffuse, mild uptake in both lungs and the spleen.
View Article and Find Full Text PDFSingle-incision laparoscopic splenectomy and splenic autotransplantation for an enlarged wandering spleen with torsion.
European J Pediatr Surg Rep
June 2014
Department of Surgery and Clinical Science, Yamaguchi University Graduate School of medicine, Ube, Yamaguchi, Japan.
A wandering spleen is a rare condition in which the spleen is not located in the left upper quadrant, but instead is found in the lower abdomen or in the pelvic region because of the laxity of the peritoneal attachments. The unusually long pedicle is susceptible to twisting, which can lead to ischemia, and eventually to necrosis. We herein report a case of an enlarged wandering spleen with torsion, successfully treated by single-incision laparoscopic splenectomy and autotransplantation.
View Article and Find Full Text PDFDetection of melanoma lesions using ¹³¹I-IMBA obtained by electrophilic substitution of ¹³¹I for metal organic substituent - a preliminary communication.
Nucl Med Rev Cent East Eur
December 2011
Department of Nuclear Medicine, Chair of Medical Imaging, Medical University of Lodz, Poland.
Background: Compounds of N-alkylated benzamide derivatives have been the subject of investigations in the last few decades from the standpoint of their possible application for scintigraphic detection of melanoma. Positive results have been observed in studies on biodistribution when using animal models and the compound IMBA (N-(2-diethylaminoethyl)-3-iodo-4-metoxybenzamide). The present study presents preliminary results of scintigraphic studies in patients with documented melanoma metastases, who were administered ¹³¹I-IMBA synthesized by modified labelling procedure (electrophilic substitution of radioactive ¹³¹I to metal organic substituent).
View Article and Find Full Text PDF[The formation of infliximab and anti-infliximab immune complexes as an explanation for non-responding to infliximab treatment of rheumatoid arthritis: observational study in 4 patients].
Ned Tijdschr Geneeskd
July 2008
Afd. Reumatologie, VU Medisch Centrum, Amsterdam.
Objective: To investigate the in vivo mechanism of non-responding to infliximab treatment of patients with rheumatoid arthritis (RA) and the role of anti-infliximab antibodies by using radiolabeled infliximab.
Design: Descriptive and comparative study.
Method: Two responding and two non-responding RA patients were infused with radiolabeled infliximab.
[Assessment for the image interpretation of 111In-ibritumomab tiuxetan in the phase II study of 90Y-ibritumomab tiuxetan in patients with relapsed or refractory indolent B-cell lymphoma].
Kaku Igaku
May 2008
Department of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School of Medicine.
Prior to the 90Y-ibritumomab tiuxetan (Y2B8) therapy, imaging is performed to verify the expected biodistribution of 111In-ibritumomab tiuxetan (In2B8). In order to determine the indication of radioimmunotherapy with Y2B8, the interpretation criteria for altered biodistribution of In2B8 was established. A phase II study of Y2B8 in patients with relapsed or refractory indolent B-cell lymphoma was performed in nine institutions in Japan.
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