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Improvement of flipped classroom teaching in colleges and universities based on virtual reality assisted by deep learning.
Sci Rep
January 2025
School of Electronic and Information Engineering, Changsha Institute of Technology, Changsha, 410200, China.
In order to solve the limitations of flipped classroom in personalized teaching and interactive effect improvement, this paper designs a new model of flipped classroom in colleges and universities based on Virtual Reality (VR) by combining the algorithm of Contrastive Language-Image Pre-Training (CLIP). Through cross-modal data fusion, the model deeply combines students' operation behavior with teaching content, and improves teaching effect through intelligent feedback mechanism. The test data shows that the similarity between video and image modes reaches 0.
View Article and Find Full Text PDFFluid flow impacts endothelial-monocyte interactions in a model of vascular inflammatory fibrosis.
Sci Rep
January 2025
Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA.
The aberrant vascular response associated with tendon injury results in circulating immune cell infiltration and a chronic inflammatory feedback loop leading to poor healing outcomes. Studying this dysregulated tendon repair response in human pathophysiology has been historically challenging due to the reliance on animal models. To address this, our group developed the human tendon-on-a-chip (hToC) to model cellular interactions in the injured tendon microenvironment; however, this model lacked the key element of physiological flow in the vascular compartment.
View Article and Find Full Text PDFPositive feedback loop involving AMPK and CLYBL acetylation links metabolic rewiring and inflammatory responses.
Cell Death Dis
January 2025
NHC Key Laboratory of Advanced Reproductive Medicine and Fertility (China Medical University), National Health Commission, Shenyang, 110004, China.
Metabolic rewiring underlies effective macrophages defense to respond disease microenvironment. However, the underlying mechanisms driving metabolic rewiring to enhance macrophage effector functions remain unclear. Here, we demonstrated that the metabolic reprogramming in inflammatory macrophages depended on the acetylation of CLYBL, a citramalyl-CoA lyase, at lysine 154 (K154), and blocking CLYBL-K154 acetylation restricted the release of pro-inflammatory factors.
View Article and Find Full Text PDFThe Chinese version of the patients' experiences scale for older inpatients in the medical group: Instrument development and cross-sectional validation study.
Geriatr Nurs
January 2025
West China Biomedical Big Data Center, West China Hospital of Sichuan University, Chengdu, China. Electronic address:
Value-based healthcare is increasingly emphasizing attention to patients' self-reported experiences. However, due to the lack of effective tools, older patients in China lack feedback on the comprehensive care experience. Based on the psychometric assessment procedure, we developed a new geriatric inpatient experience scale (GIES).
View Article and Find Full Text PDFRevisiting the electrophysiological correlates of valence and expectancy in reward processing - A multi-lab replication.
Cortex
January 2025
Department of Experimental Clinical & Health Psychology, Ghent University, Ghent, Belgium.
Two event-related brain potential (ERP) components, the frontocentral feedback-related negativity (FRN) and the posterior P300, are key in feedback processing. The FRN typically exhibits greater amplitude in response to negative and unexpected outcomes, whereas the P300 is generally more pronounced for positive outcomes. In an influential ERP study, Hajcak et al.
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