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[Individual systemic reactions of human organism under acute hypoxia].
Ross Fiziol Zh Im I M Sechenova
November 2012
Results of physiological and biochemical study including analysis of brain electrical activity dynamics, volumetric and linear parameters of cerebral blood flow, plasma stress hormones levels (adrenaline, noradrenaline, cortisol) and energy metabolism markers (glucose, lactate) at different stages of acute normobaric hypoxia are presented. The correlations are shown between alterations of main cerebral arteries tone and resistivity type vessels, as well as between changes in linear and volumetric cerebral blood flow providing a compensation of the oxygen deficit. Features of EEG dynamics were investigated that characterized CNS regulatory functions and brain electrogenesis disturbance under deep stages of hypoxia.
View Article and Find Full Text PDF[EEG pattern as an instrument for evaluation of neurophysiological mechanisms underlying adaptation disorders].
Zh Vyssh Nerv Deiat Im I P Pavlova
July 2005
The method of statistical evaluation of probable interaction between the main constituents of bioelectrical activity of the brain (BEA) enables to reveal the character of intercentral relations both under normal conditions and at adaptation disorders of different severance. Several types of statistic interactions have been revealed between EEG components (SSIC) correlating with normal interrelations between cortex and subcortex, level of preferential involvement of non-specific brain formations (cortex, thalamic, hypothalamic and brain-stem) into the process, and the degree of instability of neuro-dynamic processes. The findings obtained have shown the degree of expression of adaptation disorders to be connected with gradual destruction of "functional nuclear" within alpha-range, amplification of statistical interrelations with beta-EEG and teta-EEG components and formation of pathological nuclear structures within the ranges aforesaid.
View Article and Find Full Text PDFDynamic changes of speech function were studied in patients with persistence aphatic disorders after stroke under the conditions of application of V2 vasopressin receptor agonist (1-desamino-8-D-arginin-vasopressin). A course of intranasal administration of the medical drug by using the double blind control showed a reliable reduction of frustration severity of expressive and impressive speech in patients with aphasias of different forms and degrees. A correlation of positive influence of vasopressin on speech, verbal memory and attention was found at efferent motor aphasias.
View Article and Find Full Text PDF[The characteristics of the slow electrical activity of the brain in those who worked in the cleanup of the aftermath of the accident at the Chernobyl Atomic Electric Power Station].
Izv Akad Nauk Ser Biol
September 1999
Semenov Institute of Chemical Physics, Russian Academy of Sciences, Moscow, Russia.
We studied the slow electrical activity of the brain in people subjected to irradiation as a result of the Chernobyl accident and in healthy donors. The mean constant potential, which is an index of energy metabolism in different regions of the cerebral cortex, is reliably lower in eliminators, as compared to the donors, thus suggesting a postradiation energy deficiency of the brain. The structure of correlations between the constant potential indices is different: the number of significant correlations in the group of eliminators is lower by 30% than in the group of donors, thus suggesting disturbed intercentral relations in the CNS under the conditions of postradiation energy deficiency of the brain.
View Article and Find Full Text PDF[Neuro-ontogenic factors in the pathogenesis of febrile seizures in children during the first year of life].
Zh Nevrol Psikhiatr Im S S Korsakova
October 1998
Sensomotor development, periods of febrile attacks (FA), spectral EEG characteristics in narrow range of frequency were examined in 12 healthy children and 34 children with FA. There was a correlation between FA debute, relapse and physiologic formation and change of sensomotor rhythm on months 4-5, 7-8, 11-12 of life. The correlation was also established between a decrease of sensomotor reactivity of child, neocortical activation with repeated FA as well as transformation of the attacks' structure.
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