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Work loss in patients with rheumatoid arthritis treated with abatacept, rituximab, tocilizumab or TNF inhibitors: a nationwide direct drug-to-drug comparison.
RMD Open
January 2025
Clinical Epidemiology Division, Dept of Medicine, Karolinska Institutet, Stockholm, Sweden.
Objective: To compare work loss after starting tumour necrosis factor inhibitors (TNFi), rituximab, abatacept or tocilizumab in patients with rheumatoid arthritis (RA).
Methods: We used data from the Swedish Rheumatology Quality Register to identify patients aged 19-62 years who were treated with TNFi (n=15 093), rituximab (n=2123), abatacept (n=1877) or tocilizumab (n=1720) between 2007 and 2020. Data on work loss (0-365 days per year) from sick leave and disability pension were retrieved from linkage to the Social Insurance Agency.
Accuracy of latest large language models in answering multiple choice questions in dentistry: A comparative study.
PLoS One
January 2025
Faculty of Dentistry, PHENIKAA University, Hanoi, Vietnam.
Objectives: This study aims to evaluate the performance of the latest large language models (LLMs) in answering dental multiple choice questions (MCQs), including both text-based and image-based questions.
Material And Methods: A total of 1490 MCQs from two board review books for the United States National Board Dental Examination were selected. This study evaluated six of the latest LLMs as of August 2024, including ChatGPT 4.
CTCs Detection Methods In Vivo and In Vitro and Their Application in Tumor Immunotherapy.
J Surg Oncol
January 2025
Department of Plastic Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Circulating tumor cells (CTCs) are tumor cells that detach from the primary tumor site and enter the bloodstream. They hold significant value for the early detection, diagnosis, and treatment of tumors. CTC detection methods can be classified into in vivo and in vitro techniques.
View Article and Find Full Text PDFNeonatal outcomes in twin pregnancies in Finland from 2008 to 2023.
Eur J Pediatr
January 2025
Institute of Clinical Medicine and Department of Pediatrics, University of Eastern Finland, Kuopio, Finland.
Unlabelled: Twin pregnancies are associated with higher risks of adverse maternal and neonatal outcomes compared to singleton pregnancies. This retrospective nationwide cohort study analyzed trends in twin pregnancy outcomes in Finland from 2008 to 2023 using data from the Finnish Medical Birth Register. Outcomes assessed included perinatal mortality, stillbirths, neonatal mortality, neonatal intensive care unit (NICU) admissions, and hospitalization rates at one week of age.
View Article and Find Full Text PDFCommon and distinct neural patterns of gray matter alterations in adults with anorexia nervosa and obsessive-compulsive disorder.
Eur Arch Psychiatry Clin Neurosci
January 2025
Lanzhou University Second Hospital, Lanzhou, China.
Anorexia nervosa (AN) and obsessive-compulsive disorder (OCD) often share multiple similar symptoms and are highly comorbid; however, the common and distinct brain neuroanatomy of these two diseases are unclear. The current study attempted to identify the overlapping and different gray matter volume (GMV) between AN and OCD. We conducted a voxel-wise meta-analysis of GMV using the latest Seed-based d Mapping with Permutation of Subject Images Toolbox (SDM-PSI) software.
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