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Thymol inhibits ergosterol biosynthesis in Nakaseomyces glabratus, but differently from azole antifungals.
J Mycol Med
December 2024
Invasive Fungi Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran; Department of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran. Electronic address:
Introduction: Nakaseomyces glabratus is considered a high priority of attention according to WHO, and also is an important yeast species due to its high rate of intrinsic/acquired resistance against fluconazole. This study aimed at the possible mechanisms of action of thymol, as the promising new antifungal agent, in N. glabratus.
View Article and Find Full Text PDFComparative efficacy of plant derived extracts with the insecticide mospilan on two whitefly species Bemisia tabaci biotype B and Trialeurodes ricini.
Sci Rep
January 2025
Forestry and Wood Technology Department, Faculty of Agriculture, Alexandria University, Alexandria, 21545, Egypt.
The insecticidal, synergistic, and acetylcholinesterase (AChE) inhibitory effects of plant n-hexane extracts (HEs) were evaluated. The HEs from thyme (Thymus vulgaris L.) leaves, garlic (Allium sativum L.
View Article and Find Full Text PDFThymol and Carvacrol as Potential Tocolytic and Anti-inflammatory Agents in Pregnant Rat Uterus.
Curr Mol Pharmacol
January 2025
Área Académica de Medicina del Instituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Pachuca, Hidalgo, México.
Introduction: This work aimed to evaluate the anti-inflammatory and myorelaxant effect of thymol (TM) and carvacrol (CAR) in the pregnant rat uterus. Both compounds exhibit considerable antimicrobial, antispasmodic, and anti-inflammatory effects and due to these properties, they were studied in this in vitro model of premature birth induced by infection.
Method: All uterine tissues were studied in uterine contraction tests to determine the inhibitory effect of TM, CAR (10, 56, 100, 150, and 230 μM), and nifedipine (a calcium channel antagonist) on phasic and tonic contraction induced by electro- and pharmacomechanical stimuli.
Improper storage methods cause food resources to be wasted, and the development of multifunctional intelligent packaging can realize freshness monitoring and extend the shelf life. In this study, an intelligent alizarin/thymol-loaded polycaprolactone/gelatin/zein nanofibrous film was prepared and achieved the dual functions of pH-responsive and antibacterial properties. The film was fabricated using electrospun technology and characterized by SEM, FT-IR, WCA, TGA, DSC, and mechanical property tests, which had good antioxidant properties (81.
View Article and Find Full Text PDFNano Silicon Modulates Chemical Composition and Antioxidant Capacities of Ajowan () Under Water Deficit Condition.
Foods
January 2025
Department of Food Chemistry and Biocatalysis, Wrocław University of Environmental and Life Sciences, 50-375 Wrocław, Poland.
Ajowan () is an important spice in the food industry, as a well as a medicinal plant with remarkable antioxidant properties. In this study, its essential oil content, chemical composition, flavonoid content, phenolic content, and antioxidant capacity were evaluated under three irrigation regimes (50, 70, and 90% field capacity) and different amounts of nano silicon (0, 1.5, and 3 mM) in ten populations of ajowan.
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