Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1620/tjem.86.77 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Antihypertensive and Angiotensin I-Converting Enzyme-Inhibitory Effects of the Leaves of Sesamum indicum and Bioactive Compounds.
Chem Pharm Bull (Tokyo)
December 2024
Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Nagasaki International University.
Sesame (Sesamum indicum L.) is an important oilseed crop, and its seeds are a source of edible oil and widely used as a nutritious food that is beneficial to health in oriental countries. Phytochemical and biological investigations of the seeds have been well reported; however, those of the leaves have been limited.
View Article and Find Full Text PDFAssociation between Angiotensin-converting enzyme (ACE) insertion/deletion polymorphism and hypertension in a Ghanaian population.
PLoS One
December 2024
Department of Biomedical Sciences, University for Development Studies, Tamale, Ghana.
Background: Genetic modifications in the renin-angiotensin aldosterone system (RAAS) have been suggested to play a key role in the pathophysiology of hypertension. The insertion/deletion polymorphism of angiotensin-converting enzyme (ACE) gene phenomenon and its relationship with essential hypertension has not been explored within the Ghanaian population. This study aims to determine the relationship between the ACE I/D polymorphism and the risk of essential hypertension among patients seeking medical attention.
View Article and Find Full Text PDFComparison of Gene Polymorphisms of ACE1 and ACE2 and the Level of Total ACE Activity in the Blood of Afghans and Iranians with COVID-19 and Its Relationship with Disease Severity.
Viral Immunol
December 2024
Department of Clinical Biochemistry, Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Field evidence indicates differences in the rate and severity of COVID-19 infection among Afghans and Iranians, potentially influenced by individual genomic variances. Therefore, investigating the potential causes of these disparities holds significant clinical importance. This study aims to explore and compare variations in the genes encoding angiotensin-converting enzyme 1 (ACE1) and angiotensin-converting enzyme 2 (ACE2), along with total ACE activity levels in the blood of Afghans and Iranians with COVID-19, to assess any potential correlation with disease severity.
View Article and Find Full Text PDFBMY 7378, a selective α-adrenoceptor antagonist, is a new angiotensin converting enzyme inhibitor: In silico, in vitro and in vivo approach.
Biochim Biophys Acta Gen Subj
January 2025
Unidad de Investigación en Biomedicina, Carrera de Enfermería, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Av. de los Barrios 1, Los Reyes Iztacala, Tlalnepantla 54090, Estado de México, México. Electronic address:
BMY 7378 is a multitarget drug primarily known for its selective antagonism of α-adrenoceptors (α-AR), exhibiting both hypotensive effects and the ability to prevent or reverse angiotensin II-induced vascular hypertrophy. Notably, BMY 7378 contains a phenylpiperazine moiety, a structural feature associated with angiotensin-converting enzyme (ACE) inhibition. This study aimed to investigate ACE inhibition as a potential pharmacological mechanism of BMY 7378.
View Article and Find Full Text PDFComparison of athletic performance of Turkish ice hockey players with ACE I/D (rs1799752), ACTN3 (rs1815739), PPARA (rs4253778) and HIF1A (rs11549465) polymorphisms.
Cell Mol Biol (Noisy-le-grand)
November 2024
Marmara University, Faculty of Dentistry, Department of Medical Biology and Genetics, 34854, Istanbul, Turkey.
Our study is aimed at examining the Ice Hockey National Team players with regard to ACE I/D (rs1799752), ACTN3 (rs1815739), PPARA (rs4253778) and HIF1A (rs11549465) polymorphisms and physical tests. This study was participated by 21 players from ice hockey national team. While ACE I/D (rs1799752) polymorphism was obtained using conventional polymerase chain reaction method (PCR), ACTN3 (rs1815739), PPARA (rs4253778) and HIF1A (rs11549465) polymorphisms were produced by real time polymerase chain reaction method (qPCR).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!