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http://dx.doi.org/10.1093/brain/88.3.435 | DOI Listing |
Ann Indian Acad Neurol
November 2024
Department of Microbiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Cureus
October 2024
Department of Diagnostic Pathology, Kobe University Hospital, Kobe, JPN.
Mixed epithelial and stromal tumor of the kidney (MESTK) is a rare renal tumor characterized by both cystic and solid components. Although typically benign, its components can undergo malignant transformation, manifesting as a sarcomatous feature. Carcinomatous transformations are exceedingly rare.
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September 2024
Department of Internal Medicine, Aga Khan University Hospital, Nairobi, KEN.
Leptomeningeal carcinomatosis (LMC) is a rare and fatal complication associated with various solid tumors and hematological malignancies. It presents significant diagnostic challenges due to its nonspecific symptoms and complex clinical course. This case report details the presentation, diagnosis, and implications of LMC in a 33-year-old male with a history of colorectal cancer (CRC) and hemicolectomy.
View Article and Find Full Text PDFFront Oncol
August 2024
Provincial Clinical Medical College of Fujian Medical University, Department of Pathology, Fujian Provincial Hospital, Fuzhou, China.
Int J Surg Pathol
July 2024
Department of Cellular Pathology, Guy's & St Thomas' NHS Foundation Trust, London, UK.
Metaplastic thymoma is a rare thymic neoplasm that has generally been considered to follow a benign to indolent clinical course; however, 3 metaplastic thymomas with high-grade malignant transformation to sarcomatoid carcinoma have been reported. In recent years, both conventional metaplastic thymomas and this subset showing malignant transformation have been associated with recurrent fusions. We report a metaplastic thymoma showing transformation to squamous cell carcinoma, that to our knowledge is the fourth reported in the literature with transition to overtly malignant features and the first showing pure carcinomatous transformation, and in which fusion was demonstrated via next generation sequencing.
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