Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Arsenic efflux and bioremediation potential of Klebsiella oxytoca via the arsB gene.
PLoS One
January 2025
Molecular Virology Labs, Department of Biosciences, Comsats University Islamabad, Islamabad, Pakistan.
Arsenic-resistant Klebsiella oxytoca strain AT-02 was isolated from the ground water of the Multan region of Pakistan. The strain displayed high arsenite and arsenate resistance as minimal inhibitory concentration (MIC) was 600ppm and 10,000ppm respectively. The high tolerance of the isolated strain towards arsenate can be postulated due to significant increase in biofilm in response to arsenate.
View Article and Find Full Text PDFAntileishmanial and Antitrypanosomal Trends of Synthetic Tetralone Derivatives.
Drug Dev Res
February 2025
Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Aljouf, Saudi Arabia.
Leishmaniasis and trypanosomiasis are parasitic diseases that are closely linked to poverty, pose significant local burdens, and are common in tropical and subtropical regions. Various synthetic tetralone derivatives were studied as potential scaffolds for antileishmanial and antitrypanosomal activities. The compounds were studied for their effectiveness against multiple kinetoplastid protozoan pathogens: Leishmania major, Leishmania mexicana, and bloodstream trypomastigotes of Trypanosoma brucei brucei.
View Article and Find Full Text PDFMajor heavy metals and human gut microbiota composition: a systematic review with nutritional approach.
J Health Popul Nutr
January 2025
Department of Clinical Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.
Background: The human gut microbiota has a critical role in several aspects of host homeostasis, such as immune development, metabolism, nutrition, and defense against pathogens during life. It can be sensitive to xenobiotics including drugs, diet, or even environmental pollutants, especially heavy metals (HMs). The findings of some previous studies are heterogeneous due to the inclusion of various types of study (human, and animal studies) and wide exposures (phthalate, bisphenol A, HMS, etc.
View Article and Find Full Text PDFDirect binding of arsenicals to nuclear transport factors disrupts nucleocytoplasmic transport.
bioRxiv
January 2025
Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, S-405 30 Göteborg, Sweden.
Human exposure to arsenicals is associated with devastating diseases such as cancer and neurodegeneration. At the same time, arsenic-based drugs are used as therapeutic agents. The ability of arsenic to directly bind to proteins is correlated with its toxic and therapeutic effects highlighting the importance of elucidating arsenic-protein interactions.
View Article and Find Full Text PDFSalt use patterns and heavy metal urinary excretion.
Front Nutr
January 2025
Clinical Center of Reproductive Medicine, Lianyungang Maternal and Child Health Hospital, Lianyungang, China.
Background: Salt usage patterns have been associated with a risk of multiple diseases; however, their relationship with heavy metal exposure has not been extensively studied.
Methods: This study analyzed survey data from 11,574 NHANES participants. Weighted linear regression models were used to examine the relationship between the type of salt used by participants, the frequency of adding salt at the table, and the frequency of adding regular or seasoned salt to cooking or food preparation, and urinary concentrations of 10 heavy metals.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!