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On the pursuit of reproducibility: the importance of large sample sizes in psychoimmunology.
Transl Psychiatry
January 2025
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Peripheral inflammatory markers (PIMs), such as C-reactive protein (CRP) or white blood cell count (WBC), have been associated with depression severity in meta-analyses and large cohort studies. However, in typically-sized psychoimmunology studies (N < 200) that explore associations between PIMs and neurobiological/psychosocial constructs related to depression and studies that examine less-studied PIMs (e.g.
View Article and Find Full Text PDFResearch progress in the etiology and minimally invasive therapy of hallux valgus.
Surgeon
January 2025
Department of Arthritis, Affiliated Hospital of Shandong Second Medical University, 2428 Yuhe Road, Kuiwen District, Weifang City, Shandong Province, 261031, PR China. Electronic address:
Hallux valgus (HV) is the most common foot deformity. It has various pathogenic factors that make its pathogenesis challenging to understand. As the disease progresses, patients experience amplified pain and decreased activities, significantly affecting their quality of life.
View Article and Find Full Text PDFImaging of Pulmonary Vasculitis.
Radiol Clin North Am
March 2025
Cardiopulmonary Imaging Section, Department of Radiology, University of Alabama at Birmingham, JTN 361, 619 19th Street South, Birmingham, AL 35294, USA. Electronic address:
This review will describe various disease processes resulting in pulmonary vasculitis. The clinical and imaging findings in these diseases often overlap with diffuse alveolar hemorrhage secondary to pulmonary capillaritis, a common manifestation in many of these diseases. A multidisciplinary approach is important for the correct diagnosis of these diseases, and this review will highlight the important imaging findings that radiologists need to be aware of to aid in this diagnostic process.
View Article and Find Full Text PDFThe Pediatric Hip Physical Exam.
Curr Rev Musculoskelet Med
January 2025
UCSF Department of Orthopaedic Surgery, 500 Parnassus Ave, MU 320W, San Fransciso, CA, 94143, USA.
Purpose Of Review: Atraumatic hip pain in children is one of the most common orthopaedic complaints in this population. This review details the important elements of the pediatric hip physical exam and provides an overview of pertinent clinical exam findings in specific diagnoses of common pediatric hip pathology.
Recent Findings: A thorough physical exam is critical for the diagnosis of pediatric hip pathology, as many conditions have exam findings that are very commonly associated with the pathology, if not pathognomonic for the disorder.
Estimating Total-Tract Digestibility of Nutrients and Their Contribution to Digestible Energy Supplies in Equine Diets.
J Equine Vet Sci
January 2025
School of Animal Sciences, Virginia Polytechnic Institute and State University, 175 West Campus Dr., Blacksburg, VA, USA, 24061. Electronic address:
Our objectives were to use a quantitative literature review to explore dietary and feed factors influencing apparent total-tract digestibility of dry matter (DMD), crude protein (CPD), neutral detergent fiber (NDFD), ether extract (EED), non-structural carbohydrates (NSCD), non-fiber carbohydrates (NFCD), and residual organic matter (rOMD) in equine diets, and to assess their contributions to digestible energy (DE) supplies. Data from 54 studies were modeled using linear mixed-effect regressions, with publication as a random effect to account for study variability. For each nutrient, five models were derived with explanatory variables including: dry matter intake (DMI; % BW/day) and DM (% as-fed), and dietary components (CP, organic matter, EE, NDF, acid detergent fiber, NSC, starch, and NFC as % of DM), and feed types (forage, non-forage fiber, legumes, cereal, and oil proportions).
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