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Br J Anaesth
March 2025
Departamento de Ciencia de la Computación, Facultad de Ingeniería, Pontificia Universidad Católica de Chile, Santiago, Chile.
Pulse oximetry, although generally effective under ideal conditions, faces challenges in accurately estimating peripheral oxygen saturation (SpO) in complex clinical scenarios, particularly at lower saturation levels and in patients with darker skin pigmentation. Artificial intelligence (AI) offers the potential to improve SpO monitoring by enabling more accurate, equitable, and accessible estimations. We highlight key challenges in developing AI-enhanced pulse oximetry, including the need for diverse and representative datasets, refined validation protocols addressing ethical concerns such as algorithmic bias, expanded SpO measurement ranges encompassing hypoxaemic levels, and enhanced model interpretability.
View Article and Find Full Text PDFJ Rheumatol
March 2025
R. Aggarwal, MD, MS, UPMC Myositis Center, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Idiopathic inflammatory myopathies (IIMs) comprise a spectrum of autoinflammatory disease characterized primarily by muscle inflammation, with secondary involvement of diverse organs including joints, skin, lungs, heart, and the gastrointestinal system. Managing these conditions poses considerable challenges, often inflicting profound distress on the afflicted individuals. Encouragingly, the deployment of chimeric antigen receptor (CAR) T cell therapy has demonstrated promising efficacy across various autoimmune diseases, extending hope for ameliorating the burden of IIM.
View Article and Find Full Text PDFPlant Sci
March 2025
International Crops Research Institute for the Semi-Arid Tropics (ICRISAT), Telangana 502324, India. Electronic address:
Blanching is the process of removing the testa or seed coat (skin) from peanuts, and a genotype's capacity to release its testa is referred to as its blanchability. The genotype, seed quality, harvest date, level of maturity, as well as the length of time and temperature of the post-harvest storage period, are said to have an impact on the peanut's blanchability. This characteristic is of enormous economic significance in the production of food items made from peanuts.
View Article and Find Full Text PDFBackground: Carotenoid levels measured in the skin and retina are increasingly being used as biomarkers of general health, function, and disease. Whether they are directly interchangeable, however, is not clear. Several previous studies comparing the measures in adults and children have found inconsistent results.
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