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Simultaneous pancreas-kidney (SPK) transplantation is a recognized treatment for patients with insulin-dependent diabetes and advanced chronic kidney disease or end-stage renal disease (ESRD), offering significant survival benefits. However, it is associated with a higher risk of venous thrombosis, which can jeopardize the survival of the pancreaticoduodenal graft. This case report describes a patient with type 2 diabetes, hypertension, and ESRD who developed acute, occlusive deep vein thrombosis (DVT) involving the right common femoral, profunda femoral, and greater saphenous veins on postoperative day 1 (POD1) following a deceased donor SPK transplant, despite systemic prophylactic anticoagulation.
View Article and Find Full Text PDFTiming of Iliofemoral Vein Stent Implantation after Mechanical Thrombectomy for Acute Iliofemoral Venous Thrombosis.
Ann Vasc Surg
December 2024
Department of General Surgery, 218 Jixi Road, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China. Electronic address:
Objectives: Comparison of the treatment effects of immediate stent implantation vs staged stent implantation after AngioJet mechanical thrombectomy in patients with acute iliofemoral venous thrombosis.
Methods: A study included 80 patients with acute iliofemoral venous thrombosis formed between June 2021 and February 2023. They were divided into two groups: the direct implantation group (37 patients, 9 males) and the staged implantation group (43 patients, 10 males).
Post-Thrombotic Syndrome Morbidity in Mechanical Thrombectomy Versus Pharmacomechanical Catheter-Directed Thrombolysis of Iliofemoral Deep Venous Thrombosis.
Ann Vasc Surg
November 2024
Division of Vascular Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA.
Article Synopsis
- Iliofemoral deep venous thrombosis is linked to post-thrombotic syndrome (PTS), and two main treatments are pharmacomechanical catheter-directed thrombolysis (PCDT) and mechanical thrombectomy (MT) with large-bore devices.
- A study analyzed 349 patients from 2007 to 2022, comparing PCDT and MT, focusing on PTS rates, vessel patency, and other outcomes, finding no significant differences in PTS rates between the two treatment groups.
- MT patients had better logistical outcomes, including greater likelihood of a single operating room visit and shorter ICU stay, but it was not associated with increased PTS risk or higher Villalta scores.
Case report of simultaneous phlegmasia cerulea dolens and acute limb ischemia.
Int J Surg Case Rep
December 2024
Department of Vascular surgery, University hospital of Bratislava, Faculty of Medicine - Comenius University, Slovak Republic.
Article Synopsis
- Phlegmasia cerulea dolens (PCD) is a serious condition caused by massive deep vein thrombosis that can threaten both life and limbs, often requiring urgent treatment options such as endovascular therapy or surgical embolectomy in specific cases.
- A patient case illustrated simultaneous PCD with acute limb ischemia, showing symptoms like abdominal pain, cyanosis, and motor deficits, leading to a successful combined surgical embolectomy to resolve the issues.
- This report emphasizes that there are no formal guidelines for treating PCD and stresses the necessity for personalized treatment strategies and comprehensive care access.
Rationale and design of the DEFIANCE study: A randomized controlled trial of mechanical thrombectomy versus anticoagulation alone for iliofemoral deep vein thrombosis.
Am Heart J
November 2024
Guy's and St Thomas' NHS Foundation Trust, London, UK.
Background: Deep vein thrombosis (DVT) is a common medical condition that is associated with clinically significant sequelae, including postthrombotic syndrome (PTS). Anticoagulation alone remains the guideline-recommended treatment for many patients with iliofemoral DVT. Recent technological advances have led to an increase in the use of mechanical thrombectomy for DVT, but mechanical thrombectomy-based procedures have not yet been compared with standard-of-care anticoagulation therapy in randomized studies.
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