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Radiological features characterising indeterminate testes masses: a systematic review and meta-analysis.
BJU Int
March 2023
Department of Urology, Imperial College Healthcare NHS Trust, London, UK.
Article Synopsis
- The increased use of scrotal ultrasonography (SUS) helps in detecting uncertain testicular masses, potentially preventing unnecessary surgeries like radical orchidectomy by identifying their characteristics.
- A systematic review of 32 studies with 1,692 masses aimed to classify benign and malignant testicular masses based on SUS and MRI features, using histopathology as a reference.
- Findings indicate that certain SUS characteristics, such as size and echogenicity, can significantly predict malignancy in post-pubertal males, while data on pre-pubertal cases remains limited.
Testicular tumors in the pediatric patient.
Semin Pediatr Surg
August 2021
Department of Urology, University of Kentucky, 800 Rose St., MS237, Lexington, KY 40536, USA. Electronic address:
Testicular cancer is a rare malignancy that demonstrates variability in histopathologic features, treatment protocols, and outcomes based on a patient's age at presentation. In the pediatric population, puberty provides an important timestamp for evaluating and understanding the disease process. Prepubertal males, often designated as < 11 years of age, are more likely to present with benign disease.
View Article and Find Full Text PDFUltrasound evaluation of long-term outcome in boys operated on due to testicular torsion.
Medicine (Baltimore)
May 2021
The Department of Pediatric Surgery and Traumatology.
We aimed at verifying the usefulness of spectral Doppler ultrasonography in determining development of the testis after torsion in boys.The study involved 28 patients and 30 control cases divided into 3 developmental groups: pre-pubertal, early pubertal, and pubertal. It presented surgical management in testicular torsion (TT), volume, and echogenicity of testes, as well as peak-systolic velocity (PSV), end-diastolic velocity (EDV), and vascular resistance index (RI) in the capsular and intra-testicular arteries, regarding developmental groups, detorsed testes, uninvolved ones, and testes in the control group.
View Article and Find Full Text PDFOvarian morphometrical evaluation to assess reproductive activity suppression in heavy weight finishing gilts immunized against gonadotropin-releasing hormone.
Res Vet Sci
May 2021
Department of Morphology, Institute of Biological Sciences, Federal University of Minas Gerais, Av. Antônio Carlos, 6627, 31.270-901 Belo Horizonte, MG, Brazil. Electronic address:
It is known that immunizing gilts against gonadotropin-releasing hormone (GnRH) is an efficient castration method that increases their growth performance. However, it is still unknown the ovarian histophysiology outcomes after this procedure. Therefore, the aim of this study was to investigate in detail, using morphological and morphometrical methods, changes in the ovarian structure that result in the suppression of ovarian activity, as well as to gain knowledge on the ovarian structure to assist in ovarian histopathological diagnoses.
View Article and Find Full Text PDFComplete androgen insensitivity syndrome with accelerated onset of puberty due to a Sertoli cell tumor.
Clin Pediatr Endocrinol
April 2021
Department of Endocrinology and Metabolism, Aichi Children's Health and Medical Center, Aichi, Japan.
Article Synopsis
- - Complete androgen insensitivity syndrome (CAIS) results from mutations in the androgen receptor gene, presenting as a 46,XY karyotype with male gonads but normal female external genitalia.
- - Although patients with CAIS have a low risk of gonadal tumors before puberty, that risk increases with age, and most tumors typically arise from germ cells rather than stromal cells.
- - This report discusses a unique case of a CAIS patient who, at 8 years old, showed signs of early puberty due to a feminizing Sertoli cell tumor, which was confirmed after a gonadectomy at age 10.
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