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Demographic and Clinical Characteristics of Benign Laryngeal Lesions: Insights from a Decade of Experience in a Tertiary Hospital.
Niger Med J
January 2025
Department of Clinical Services, National Ear Care Centre, Kaduna, Nigeria.
Background: Benign laryngeal lesions, characterized by non-cancerous growths in the larynx, significantly impact voice quality and respiratory function. These lesions, which include vocal cord polyps, nodules, papillomas, and cysts, often result from factors such as vocal abuse, viral infections, and chronic inflammation. While studies on benign laryngeal lesions are well-documented globally, data specific to Northern Nigeria remains sparse.
View Article and Find Full Text PDF"A systematic literature review of the epidemiology, clinical, economic and humanistic burden in recurrent respiratory papillomatosis".
Respir Res
December 2024
MSD, Puteaux, France.
Introduction: Recurrent respiratory papillomatosis (RRP) is a chronic disease caused by human papillomavirus (HPV), characterized by recurrent papillomas in the respiratory tract. Presenting as either juvenile-onset RRP (JoRRP) or adult-onset RRP (AoRRP), the severity of the disease is subjective and unpredictable. Lack of curative therapies necessitates disease management involving repeated surgical removal of lesions.
View Article and Find Full Text PDFTrends in the incidence and prevalence of juvenile-onset recurrent respiratory papillomatosis following implementation of national HPV vaccination initiatives: a systematic review.
Acta Otolaryngol
January 2025
Department of Otorhinolaryngology, Head and Neck Surgery, and Audiology, Rigshospitalet, Copenhagen, Capital Region, Denmark.
Article Synopsis
- Infection with low-risk HPV types 6 and 11 can cause recurrent respiratory papillomatosis (JoRRP) in children, which leads to benign growths in the larynx.
- A systematic review studied the effects of national HPV vaccination programs on the incidence and prevalence of JoRRP, analyzing data from four studies that included 622 patients from countries like Australia, New Zealand, and the U.S.
- Results showed a significant decline in JoRRP cases after vaccination, with higher vaccination rates linking to lower disease burden, highlighting the importance of widespread HPV vaccination for future health outcomes.
[Laryngeal Papillomatosis In Niamey: Epidemiological, Diagnostic And Therapeutic Aspects].
Mali Med
November 2024
Service ORL-CCF de l'Hôpital Général de Référence de Niamey.
Objective: to present the epidemiological, diagnostic, therapeutic and progressive aspects of laryngeal papillomatosis.
Patients And Method: This was a retrospective study over a period of 6 years (January 2016 to December 2021), covering cases of laryngeal papillomatosis collected at the Oto-Rhino-Laryngology department of the Niamey National Hospital.
Results: A total of 36 cases of laryngeal papillomatosis were recorded.
Long-Term Infection With a Particular Human Papillomavirus (HPV) Genotype, HPV Subtype, or HPV Genomic Variant Does not Significantly Influence the Clinical Course of Recurrent Respiratory Papillomatosis.
J Med Virol
November 2024
Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Recurrent respiratory papillomatosis (RRP) is caused by human papillomaviruses (HPV) 6 and 11, but the role of their genomic variants in the disease's clinical course is unclear. This study investigated whether long-term persistence of a particular HPV genotype, subtype or genomic variant influences the RRP clinical course. HPV genotyping was performed in paired baseline and follow-up RRP laryngeal tissue specimens of 59 patients.
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