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Effects of Exercise Training on the Bone Marrow Immune Microenvironment and Minimal Residual Disease in Multiple Myeloma Patients Following First-Line Treatment.
Scand J Med Sci Sports
February 2025
Sports Performance Laboratory, School of Physical Education and Sport Science, National and Kapodistrian University of Athens, Athens, Greece.
The purpose of the study was to investigate the effects of exercise training on the bone marrow immune microenvironment and on minimal residual disease of multiple myeloma patients who completed first-line induction treatment. Eight multiple myeloma patients underwent 5 months of exercise training along with standard medical treatment. Eight age- and sex-matched patients who received medical treatment only, served as controls.
View Article and Find Full Text PDFUsing neuroimaging to identify sex differences in adults with sports-related concussion: a systematic review.
Brain Imaging Behav
January 2025
Royal Melbourne Institute of Technology, 124 La Trobe Street, Melbourne, VIC, 3000, Australia.
Concussion is a common injury in sports that causes neurological damage, leading to memory loss and difficulty concentrating. Insufficient recovery time may result in significant long-term harm to individuals. Several neuroimaging techniques have been used to understand the pathophysiological changes following concussion, and how long individuals need to recover before returning to play.
View Article and Find Full Text PDFResponse to functional restoration in non-specific chronic low back pain with Modic type 1 changes.
Eur Spine J
January 2025
Department of Physical Medicine and Rehabilitation, Lariboisière-Fernand Widal Hospital, Assistance Publique- Hôpitaux de Paris (AP-HP), Université Paris Cité, Paris, France.
Purpose: Little information exists on the potential differential response to functional restoration between non-specific chronic low back pain (NSCLBP) individuals with and those without Modic type 1 changes. Therefore, this case-control study investigated the response profile of NSCLBP patients with and without Modic type 1 changes undergoing functional restoration.
Methods: The present study included patients participating in a functional restoration program (day-hospital program lasting five weeks) at a French tertiary care center from 2009 to 2019.
Influence of Preoperative Depression on Cervical Spine Surgery Outcomes: A Systematic Review and Meta-Analysis.
Global Spine J
January 2025
Department of Neurological Surgery, Washington University, St. Louis, MO, USA.
Study Design: Systematic review and Meta-analysis.
Objectives: To quantify the association of preoperative depression on patient reported outcome measures (PROMS) after cervical spine surgery.
Methods: We systematically searched PubMed, Cochrane, Embase, Scopus, PsychInfo, Web of Science, and ClinicalTrials.
Dynamics and regulatory roles of RNA mA methylation in unbalanced genomes.
Elife
January 2025
Key Laboratory of Cell Proliferation and Regulation Biology of Ministry of Education, College of Life Sciences, Beijing Normal University, Beijing, China.
-methyladenosine (mA) in eukaryotic RNA is an epigenetic modification that is critical for RNA metabolism, gene expression regulation, and the development of organisms. Aberrant expression of mA components appears in a variety of human diseases. RNA mA modification in has proven to be involved in sex determination regulated by and may affect X chromosome expression through the MSL complex.
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