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Lumbar Spine Injuries in Recreational Athletes: A Review.
J Am Acad Orthop Surg
January 2025
From the Department of Orthopaedic Surgery (Dr. Hsu), Northwestern University Feinberg School of Medicine, Chicago, IL, the Department of Orthopaedic Surgery, Atrium Health (Dr. Turk), Carolinas Medical Center, Charlotte, NC, and the OrthoCarolina Spine Center (Dr. Spector), Charlotte, NC.
Back pain that is associated with lumbar spine pathology is a growing issue in the athlete population. As an aging population continues to remain active, it is essential for primary care physicians, general orthopaedic surgeons, and spine surgeons alike to understand the nuances of diagnosis and management in the recreational athlete population. This is a unique population due to the increased importance placed on returning to high levels of activity, but, by definition, they enjoy less resources and financial incentive to optimize their rehabilitation and return to sport compared with professional athletes.
View Article and Find Full Text PDFWomen's Menopausal Experiences in the UK: A Systemic Literature Review of Qualitative Studies.
Health Expect
February 2025
Imperial College Business School, Imperial College London, London, UK.
Background: Menopause, defined as the cessation of periods for over 12 months, can have a profound impact on women in numerous ways. Understanding women's experiences of menopause can lead to improved care and support during this transformative period.
Objectives: The objective of this systematic review is to identify and summarise published qualitative studies that consider the lived experiences of women with menopause in the UK and to serve as a basis for future research in the field of menopause.
Borylative desymmetrization of multifunctional haloarenes assisted by sodium dispersion.
Chemistry
January 2025
Kobe Daigaku, Research Center for Membrane and Film Technology, 1-1 Rokkodai, Nada, 657-8501, Kobe, JAPAN.
Multiply halogenated aromatic compounds were selectively borylated by a boron alkoxide in the presence of sodium dispersion when the reaction was carried out at a low temperature, while multi-functionalization took place at an elevated temperature. The reaction of 1,4-dichlorobenzene with sodium dispersion (200-1200 mol%) in the presence of isopropyloxyboron pinacolate (120-240 mol%) afforded (4-chlorophenyl)boron pinacolate in up to 84% yield. Formation of diborylated product hardly accompanied under the reaction conditions at -78 °C for 1 h.
View Article and Find Full Text PDFA Meaning-Centered Intervention for Undergraduate Women With High Weight and Shape Concerns-Replication of a Randomized Controlled Trial.
Eur Eat Disord Rev
January 2025
Department of Clinical Psychology and Experimental Psychopathology, University of Groningen, Groningen, Netherlands.
Objective: Recent studies underscore the relevance of life meaning to the maintenance of eating disorders. A previously conducted randomized controlled trial tested a meaning-centered intervention for female university students with high weight and shape concerns. After a 6-week online intervention led by a trainer, participants in the intervention condition scored higher on life meaning and lower on eating disorder symptoms and general distress compared to a waitlist group.
View Article and Find Full Text PDF"Cell dedifferentiation" versus "evolutionary reversal" theories of cancer: The direct contest of transcriptomic features.
Int J Cancer
January 2025
Institute of Cytology, Russian Academy of Sciences, St. Petersburg, Russia.
Cell dedifferentiation is considered an important hallmark of cancer. The atavistic reversal to a unicellular-like (UC) state is a less widely accepted concept, so far not included in the conventional hallmarks. The activated expression of ontogenetically earlier and evolutionary earlier genes in cancers supports both theories because ontogenesis partially recapitulates phylogenesis during cell differentiation (the cellular biogenetic law).
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