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Bisalbuminuria in an adult with bisalbuminemia and nephrotic syndrome.
Clin Chim Acta
June 1999
Department of Pathology, University of Texas Southwestern Medical Center, Dallas 75235-9073, USA.
Bisalbuminemia (or alloalbuminemia) is a relatively rare hereditary or acquired condition characterized by the presence of two distinct albumin bands, or, less commonly, a single widened albumin band, after agarose gel electrophoresis of serum. Bisalbumins are caused by point- or chain-mutations that occur with a population frequency of 1:10,000 to 1:1000. Although no adverse clinical effects have been attributed to bisalbumins, some albumin variants have altered affinity for steroid hormones, thyroxine, or drugs.
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