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Greater Influence of Density on the Electrical Properties of an Organic Semiconductor Glass Compared to Molecular Orientation.
J Phys Chem B
January 2025
Department of Chemistry, Sungkyunkwan University, Suwon 16419, Republic of Korea.
Physical vapor deposition is widely used in the fabrication of organic light-emitting diodes and has the potential to adjust the density and orientation through substrate temperature control, which may lead to enhanced electrical performance. However, it is unclear whether this enhanced property is because of the horizontal molecular orientation or the increased density. The effects of the density and orientation on the electrical properties of a potential electron transport material, (3-dibenzo[c,h]acridin-7-yl)phenyl)diphenylphosphine oxide (TPPO-dibenzacridine), were investigated.
View Article and Find Full Text PDFTernary complex of Kaempferol-Hydroxypropyl-β-Cyclodextrin-Liposomes against hepatocellular carcinoma: Preparation, validation, pharmacokinetics and efficacy studies.
Int J Pharm
January 2025
Department of Pharmacognosy, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Science Campus, Kochi 682041 Kerala, India. Electronic address:
Kaempferol (KP), a GRAS-certified phytomolecule enrolled in Phase I trials, is reported with various biological effects including anticancer activity. However, its poor pharmacokinetic profile limits the translational utility. Studies indicate that liposomes incorporating cyclodextrin inclusion complexes improves the bioavailability of hydrophobic drugs.
View Article and Find Full Text PDFTherapeutic potential of Shilong Qingxue Granule and its extract against glutamate induced neural injury: Insights from in vivo and in vitro models.
J Ethnopharmacol
January 2025
Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, Liaoning, China; College of Pharmacy, Shenzhen Technology University, Shenzhen, Guangdong, China. Electronic address:
Ethnopharmacological Relevance: Shilong Qingxue Granule (SQG), a traditional Chinese medicine, effectively treats the secondary neurological damage and functional deficits caused by cerebral hemorrhage, though its exact mechanism remains unclear.
Aim Of The Study: This study aimed to investigate the effects of SQG and its mechanisms.
Materials And Methods: we evaluated the effects of SQG and its extracts on glutamate induced nerve damage using in vivo and in vitro models.
Toxicity of rare earth elements europium and samarium on zebrafish development and locomotor performance.
J Hazard Mater
January 2025
Key Laboratory of Physical Fitness and Exercise Rehabilitation of Hunan Province, Hunan Normal University, Changsha 410012, China. Electronic address:
Rare earth elements are integral to modern technology, but their increasing environmental distribution due to anthropogenic activities poses potential health risks to humans. This study utilized zebrafish as a model to assess developmental and locomotor performance effects of europium and samarium. Exposure to Eu or Sm induced a reduction in heart rate, growth inhibition, and morphological deformities.
View Article and Find Full Text PDFBio-fabrication of chitosan-stabilized magnesium oxide nanomaterials: Investigation of photocatalytic, in vitro cytotoxicity activities and apoptosis in oral squamous carcinoma cells.
Int J Biol Macromol
January 2025
Centre of Advanced Study in Marine Biology, Annamalai University, Parangipettai 608 502, Tamil Nadu, India.
A bio-fabrication approach is a novel way to develop chitosan-stabilized magnesium oxide nanomaterials (cMgO-NMs). The process involves utilizing polymeric chitosan as the reducing and stabilizing agent. The characteristics of the developed cMgO-NMs were determined using various spectroscopical techniques.
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