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Tissue Perfusion and Biomarkers Assessment Following Root Coverage Procedures.
J Periodontal Res
January 2025
Division of Periodontology, Department of Oral Medicine, Infection, and Immunity, Harvard School of Dental Medicine, Boston, Massachusetts, USA.
Aim: To assess tissue perfusion changes and wound healing biomarker levels after root coverage procedures with coronally advanced flap in combination with the cross-linked xenogeneic collagen matrix (CCMX), loaded either with a placebo or recombinant human platelet-derived growth factor-BB (rhPDGF).
Methods: This study was designed as a secondary analysis from a previously published clinical trial, and it assessed the tissue perfusion changes over 6 months around multiple gingival recession defects, treated with either with CCMX alone (control) or with CCMX + rhPDGF (test). High frequency Doppler ultrasonography (HFUS) scans were obtained at sites of interest at baseline, 2 weeks, 3 months, and 6 months after surgery.
Effect of caloric restriction with probiotic supplementation on body composition, quality of life, and psychobiological factors of obese men: A randomized, double-blinded placebo-controlled clinical trial.
Clin Nutr
December 2024
Postgraduate Program in Psychobiology, Federal University of São Paulo, São Paulo, SP, Brazil; Bioscience Department, Federal University of São Paulo, Santos, SP, Brazil. Electronic address:
Background & Aims: Obesity is a chronic disease characterized by an excess of fat mass. It is accompanied by a low-grade chronic systemic inflammation state that leads to numerous health disorders. To counteract this scenario, dietary-derived caloric restriction (CR) is the principal intervention for weight loss.
View Article and Find Full Text PDFEfficacy of lactoferrin supplementation in pediatric infections: A systematic review and meta-analysis.
Biochem Cell Biol
January 2025
Universidad Peruana Cayetano Heredia, Instituto de Medicina Tropical Alexander von Humboldt, Lima, Lima, Peru.
Pediatric infections account for approximately one-third of all deaths in children under 5 globally. Lactoferrin (LF) supplementation has the potential to reduce infection-related morbidity due to its antimicrobial, anti-inflammatory and immunoregulatory properties. We conducted a systematic review and meta-analysis of oral LF supplementation randomized controlled trials (RCT) in population under 18 years old.
View Article and Find Full Text PDFEngagement in a web-based intervention for individuals who committed sexual offenses against children: observational study.
BMC Psychol
January 2025
University Medical Center Göttingen, Clinic for Psychiatry and Psychotherapy - Forensic Psychiatry, Rosdorfer Weg 70, 37081, Göttingen, Germany.
Web-based interventions have been shown to be effective for various health and mental health problems. However, the effectiveness of interventions is often limited by the fact that individuals do not start or complete them. Using data from an intermediate analysis of the randomized placebo-controlled clinical trial to evaluate the effectiveness of @myTabu, the current study investigated engagement with a web-based intervention for 113 individuals convicted of child sexual abuse and/or for child sexual exploitation material.
View Article and Find Full Text PDFFourteen weeks of β-alanine supplementation and HIIT did not improve serum BDNF concentrations and Stroop test performance.
Int J Sports Med
January 2025
Physical Education.
This study aimed to investigate whether 14 weeks of β-alanine supplementation and high-intensity intermittent training improves brain-derived neurotrophic factor concentrations and cognitive aspects related to executive functions assessed by the Stroop test. Thirteen healthy and active men underwent a 4-week supplementation period (β-alanine: 6.4 g/d or a placebo) followed by 10-week supplementation combined with high-intensity intermittent training, totaling 14 weeks of intervention.
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