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Reappraisal of BRAFK601E-positive thyroid tumors in the NIFTP era.
Endocr Relat Cancer
December 2024
Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
BRAFK601E is an uncommon mutation typically found in encapsulated follicular-patterned thyroid tumors. Previous studies on BRAFK601E-positive thyroid tumors were conducted before the implementation of the non-invasive follicular neoplasm with papillary-like nuclear features (NIFTP) diagnosis. This study aimed to characterize BRAFK601E-positive tumors and evaluate changes in the diagnosis and management of these patients after the introduction of NIFTP.
View Article and Find Full Text PDFBronchial Basaloid Papillary Tumor of Uncertain Malignant Potential: A Case Report.
Int J Surg Pathol
June 2024
Department of Pathology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu Province, China.
Bronchial papillomas are benign tumors, which can be divided into different subtypes based on the cellular features. So far, no bronchial papilloma with basaloid cell features has been reported. We report a bronchial basaloid papillary tumor in a 67-year-old woman.
View Article and Find Full Text PDFReappraising imaging features of pancreatic acinar cystic transformation: be aware of differential diagnoses.
Eur Radiol
December 2024
Department of Pancreatology and Digestive Oncology, Beaujon University Hospital (APHP), CRMR PaRaDis Pancreatic Rare Diseases, Université Paris Cité, Clichy, France.
Article Synopsis
- A study was conducted to analyze the clinical and radiological characteristics of patients with suspected pancreatic acinar cystic transformation (ACT) based on available imaging data from 2003 to 2021.
- Of the 64 patients included, 53% were classified as having "certain" ACT, while 47% were "uncertain," with no significant difference in the number of imaging criteria between these groups.
- The findings indicate that the existing imaging criteria for diagnosing ACT often overlap with other conditions, suggesting that these criteria may be inadequate for making definitive diagnoses in some patients.
Surgical resection of recurrent differentiated thyroid cancer: patterns, detection, staging, and treatment of 683 patients.
Front Endocrinol (Lausanne)
January 2024
Division of Thyroid Surgery, The China-Japan Union Hospital of Jilin University, Jilin Provincial Key Laboratory of Surgical Translational Medicine, Jilin Provincial Precision Medicine Laboratory of Molecular Biology and Translational Medicine on Differentiated Thyroid Carcinoma, Changchun, Jilin, China.
Background: Despite improvements in overall survival, the recurrence of differentiated thyroid cancer (DTC) is becoming more common and remains a challenge necessitating accurate reappraisal of the patient. This study aimed to describe the characteristics, reasons, morbidity, and strategies of second operations for DTC.
Methods: This was a retrospective observational study of patients with DTC who underwent a second surgery between June 2008 and June 2021 in the Department of Thyroid Surgery at China-Japanese Union Hospital, Jilin University, P.
Pancreatic cystic neoplasms: Still high rates of preoperative misdiagnosis in the guidelines and endoscopic ultrasound era.
Surgery
December 2023
Department of General and Pancreatic Surgery, The Pancreas Institute, Verona University Hospital, Italy; Hepatopancreatobiliary and Liver Transplant Surgery, Department of Surgical, Oncological and Gastroenterological Sciences (DiSCOG), University of Padua, Italy.
Background: A wrong diagnosis of nature is common in pancreatic cystic neoplasms. The aim of the current study is to reappraise the diagnostic errors for presumed pancreatic cystic neoplasms in patients undergoing surgery.
Methods: All pancreatic resections for presumed pancreatic cystic neoplasms following international guidelines between 2011 and 2020 were analyzed.
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