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Assessment of Antibody Levels and Vaccine-induced Serologic Responses After Completion of Cancer Treatment in Pediatric Patients: A 6-Year Experience in Turkey on HAV, HBV, VZV, and MMR Vaccinations.
J Pediatr Hematol Oncol
January 2025
Department of Pediatric Oncology, Faculty of Medicine and Cancer Institute, Hacettepe University, Ankara, Turkey.
Objective: Childhood cancer treatment disrupts vaccination schedules and weakens or eliminates vaccine-induced immunity. In addition, post-treatment vaccine responses vary. This study aimed to assess post-treatment serum antibody levels and vaccine responses in children.
View Article and Find Full Text PDFThe postpartum period provides an opportunity to improve maternal and infant health, including identifying risks and completing immunization series. Research on completion of varicella and measles, mumps, and rubella (MMR) vaccine series among postpartum mothers is limited. This study examined data from mothers with public health insurance who received prenatal and postpartum care at the Mount Sinai Health System between January 1, 2021, and June 27, 2022.
View Article and Find Full Text PDFIncreased measles and rubella seroprevalence in children using residual blood samples from health facilities and household serosurveys after supplementary immunization activities in two districts in India.
Epidemiol Infect
November 2024
Indian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India.
Article Synopsis
- Residual blood specimens offer a cost-effective way to track seroprevalence changes compared to traditional household surveys, as shown in a study in India focused on measles-rubella vaccinations.
- A cross-sectional survey in Kanpur Nagar and Palghar found significant increases in rubella seroprevalence post-immunization, though measles trends were inconsistent between facility and community samples.
- Younger children in public facilities initially had lower rubella seroprevalence than those in private hospitals, but this gap disappeared after the vaccination campaign, highlighting the importance of residual specimens for public health monitoring.
The Utility of Serologic TORCH Testing During Pregnancy for Maternal-related Versus Fetal-related Indications: A Retrospective Study.
Pediatr Infect Dis J
October 2024
From the Raya Strauss Wing of Obstetrics and Gynecology, Galilee Medical Center, Nahariya, Israel.
Article Synopsis
- This study investigated the effectiveness of TORCH serology testing in pregnant women with suspected infections based on clinical signs, focusing on maternal versus fetal-related reasons for testing.
- Over 10 years, researchers analyzed data from 1,075 women, finding higher rates of TORCH infections, particularly cytomegalovirus (CMV), in those tested for maternal-related symptoms compared to those tested for fetal-related symptoms.
- The results suggest that while the overall benefits of TORCH testing for fetal issues were low, maternal symptoms should prompt testing, especially for CMV and Toxoplasma infections.
Seroprevalence and age-related susceptibility of TORCH infections in childbearing age women: A 5-year cross-sectional retrospective study and a literature review.
J Infect Public Health
October 2024
Unit of Clinical Microbiology, Department of Health Sciences, "Magna Græcia" University Hospital, 88100 Catanzaro, Italy.
Background: Serodiagnosis of TORCH infections should be performed in pre-pregnancy and reproductive-age women to prevent vertical transmission. Herein, we conducted a 5-year cross-sectional retrospective study in childbearing age women to provide prevalence data. Also, stratifying the cohort into three age groups, we identified those most susceptible to acute TORCH infections.
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