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Parsing reward sensitivity reveals distinct relationships with energy intake, metabolic markers, physical activity and fitness.
Acta Neuropsychiatr
January 2025
Division of Neuropsychopharmacology, Department of Chemistry, University of Tartu, Tartu, Tartumaa, Estonia.
Rewards are rewarding owing to their hedonic or metabolic value. Individual differences in sensitivity to rewards are predictive of mental health problems but may reflect variation in metabolic types. We have assessed the association of two distinguishable aspects of reward sensitivity, openness to rewards (the striving towards multiple rewards) and insatiability by reward (the strong pursuit and fixation to a particular reward), with measures of metabolism and activity in a longitudinal study of representative birth cohort samples.
View Article and Find Full Text PDFInteraction between nitrate and trichloroethene bioreduction in mixed anaerobic cultures.
Front Microbiol
January 2025
College of Resource and Environmental Science, Hubei University, Wuhan, China.
Bioremediation of trichloroethene (TCE)-contaminated sites often leads to groundwater acidification, while nitrate-polluted sites tend to generate alkalization. TCE and nitrate often coexist at contaminated sites; however, the pH variation caused by nitrate self-alkalization and TCE self-acidification and how these processes affect nitrate reduction and reductive dichlorination, have not been studied. This study investigated the interaction between nitrate and TCE, two common groundwater co-contaminants, during bioreduction in serum bottles containing synthetic mineral salt media and microbial consortia.
View Article and Find Full Text PDFScrub typhus association with autoimmune biomarkers and clinical implications.
PLoS Negl Trop Dis
January 2025
Department of Internal Medicine, Jeonbuk National University Medical School, Jeonju, Republic of Korea.
Background: Scrub typhus, a disease caused by Orientia tsutsugamushi, triggers systemic vasculitis and is prevalent in Eastern and Southern Asia. This study aimed to uncover the relationship between scrub typhus and autoimmune responses, focusing on antinuclear antibodies (ANAs) and the implications of elevated ANA titers during infection.
Method: Data from a total of 139 patients diagnosed with scrub typhus and 30 healthy controls were retrospectively analyzed through serum samples to assess the levels of ANAs and related autoantibodies.
Serum Immunoglobulin G Levels and Nicastrin Variation in Hidradenitis Suppurativa.
JAMA Dermatol
January 2025
Centre for Molecular Medicine and Biobanking, University of Malta, Malta.
Importance: Variation in nicastrin (NCSTN) is associated with a monogenic subtype of hidradenitis suppurativa. Dysregulation of humoral immunity has been suggested as a potential mechanistic link between NCSTN variation and hidradenitis suppurativa. There is a paucity of biomarkers that can predict disease-associated variation.
View Article and Find Full Text PDFInsulin resistance unraveled: Hormonal correlations in gestational diabetes.
J Med Biochem
November 2024
The First People's Hospital of Chengdu Shuangliu District /Sichuan University West China Airport Hospital, Department of Clinical Laboratory, Chengdu, Sichuan, China.
Background: To investigate the correlation between the variations of cortisol and insulin-like growth factor 1 (IGF1) and sex hormone binding globulin (SHBG) levels with insulin resistance and glucolipid metabolism in gestational glucose diabetics.
Methods: The study included 110 pregnant women diagnosed with gestational diabetes mellitus in the GDM group, and 130 healthy pregnant women in the control group. Data collection, examination of relevant indexes, and comparison of differences in indexes between groups were conducted.
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