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Pancreaticoduodenectomy with venous reconstruction using cold-stored vein allografts: long-term results of a single center experience.
J Hepatobiliary Pancreat Sci
January 2016
Division of General Surgery and Organ Transplantation, San Camillo-Forlanini Hospital, 87 Circonvallazione Gianicolense, 00152 Rome, Italy.
Background: The use of cadaveric vein allografts was first described by our group as a feasible option for venous reconstruction. The aim of this study was to report long-term results of this innovative technique.
Methods: Cold-stored veins harvested from donor cadavers were used as homologous grafts for venous reconstruction after vascular resection during pancreaticoduodenectomy.
Use of cold-stored vein allografts for venous reconstruction during pancreaticoduodenectomy.
J Gastrointest Surg
July 2013
Department of General Surgery and Organ Transplantation, S. Camillo Hospital, Circonvallazione Gianicolense 87, Rome, Italy.
Introduction: Venous resections and reconstructions of portal vein and/or superior mesenteric vein in course of pancreaticoduodenectomy are becoming a common practice and many surgical options have been described, from simple tangential resection and venorrhaphy to large segmental resections followed by interposition grafting. The aim of this study was to report the first experience of using fresh cadaveric vein allografts for venous reconstruction during pancreaticoduodenectomy focusing on technical feasibility and postoperative outcomes.
Methods: From January 2001 to October 2012, out of 151 patients undergoing pancreaticoduodenectomy for pancreatic head tumor, 22 (14.
Fresh vein allograft survival in dogs after cyclosporine treatment.
J Surg Res
April 1996
Creighton University School of Medicine, Department of Surgery, Omaha, NE 68178, USA.
Synthetic grafts are widely used for peripheral arterial reconstructions when autologous veins are not available, but their results have not been satisfactory. Venous allograft may be used as an alternative to synthetic prostheses. The aim of the study was to explore the immunosuppressive efficacy of Cyclosporine A (CyA) as a means of preventing venous allograft failures and rejection.
View Article and Find Full Text PDFFresh venous allografts in peripheral arterial reconstruction in dogs. Effects of histocompatibility and of short-term immunosuppression with cyclosporine A and mycophenolate mofetil.
J Thorac Cardiovasc Surg
December 1995
Rheumatology and Immunology Research Center, Laval University Medical Center, Quebec, Canada.
To date, no arterial substitute has been shown to be as effective as the autologous saphenous vein in peripheral revascularization procedures. In the present study, the venous allograft was evaluated as a vascular substitute in terms of patency and induction of host immune reactivity, whether used in major histocompatibility complex-incompatible, major histocompatibility complex-incompatible dogs. The immunosuppressive drug therapies were given for a period of 31 days, beginning 1 day before transplantation, and consisted of the use of cyclosporine A, mycophenolate mofetil, or a combination of both.
View Article and Find Full Text PDFA denaturated venous homograft as an alternative material for shunts and other reconstructions in congenital cardiac surgery.
J Cardiovasc Surg (Torino)
February 1991
Department of Thoracic and Cardiac Surgery, University Hospital St. Radboud, Nijmegen, The Netherlands.
A human venous homograft "Varivas R", in clinical use for 10 years for vascular access loops and femoropopliteal bypasses, has been used since December 1985 as a material for aortopulmonary shunts and other reconstructive procedures in congenital heart surgery. For this purpose vein segments 5 cm length, varying in diameter from 4 up to 10 mm by steps of 1 mm, were obtained. Our experience with Varivas is limited to 59 patients.
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