Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1983928 | PMC |
| http://dx.doi.org/10.1136/bmj.3.5663.178 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Stanley L Drummond-Jackson. Pioneer of intravenous anaesthesia in dentistry.
SAAD Dig
January 2011
Department of Restorative Dentistry, Liverpool University Dental Hospital, Pembroke Place, Liverpool L3 5PS.
Stanley Lithgow Drummond-Jackson was born in Northumberland and qualified from Edinburgh University Dental School in 1931. Even in the early stages of his practice he devoted his energies to the problem of pain control in dentistry, publishing his first paper in 1935. In the early 20th century most dental anaesthetics were inhalational with nitrous oxide, ether, ethyl chloride and chloroform.
View Article and Find Full Text PDFDoes glycine antagonism underlie the excitatory effects of methohexitone and propofol?
Br J Anaesth
May 1992
Clinical Pharmacology Unit, Addenbrooke's Hospital, Cambridge.
We have investigated the pharmacological basis of CNS excitation that occurs in association with general anaesthesia in mice. Propofol produced sustained clonic movements during anaesthesia. Methohexitone produced intermittent non-rhythmic jerking during anaesthesia.
View Article and Find Full Text PDFContinuous infusion of methohexital and alfentanil hydrochloride for general anesthesia in outpatient third molar surgery.
J Oral Maxillofac Surg
March 1989
Division of Oral and Maxillofacial Surgery, Duke University Medical Center, Durham, NC 27710.
Three anesthetic techniques were compared in this study: 1) Intermittent Brevital boluses supplemented with fentanyl and midazolam all titrated to patient movement, 2) constant infusion of Brevital supplemented with fentanyl and midazolam all delivered in calculated mg/kg doses based on total body weight, and 3) constant infusion of methohexital (Brevital) and alfentanil (Alfenta) supplemented by midazolam (Versed), droperidol, and glycopyrolate (Robinul) delivered in calculated mg/kg doses based on lean body mass. Nitrous oxide was delivered in all cases via nasal mask in a 30% to 50% concentration. The mean total dose of Brevital in group 1 (intermittent Brevital bolus) was 0.
View Article and Find Full Text PDFPropofol. A review of its pharmacodynamic and pharmacokinetic properties and use as an intravenous anaesthetic.
Drugs
April 1988
ADIS Drug Information Services, Manchester.
Propofol is an intravenous anaesthetic which is chemically unrelated to other anaesthetics. Induction of anaesthesia with propofol is rapid, and maintenance can be achieved by either continuous infusion or intermittent bolus injections, with either nitrous oxide or opioids used to provide analgesia. Comparative studies have shown propofol to be at least as effective as thiopentone, methohexitone or etomidate for anaesthesia during general surgery.
View Article and Find Full Text PDFClinical pharmacokinetic considerations in the treatment of increased intracranial pressure.
Clin Pharmacokinet
July 1987
Life-threatening increased intracranial pressure can be reversed by a variety of drugs. These compounds all have some disadvantages, producing rebound effects, severe coma or cardiovascular depression and electrolyte imbalance. However, reduction of intracranial pressure is a prerequisite for recovery and the benefits of treatment outweigh the risks.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!