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Safety outcome trials in four mainline medical journals 30 years apart: a narrative review and the need for the transparency of informed consents.
Trials
January 2025
Internal Medicine (Rheumatology), Academic Hospital, Istanbul, Turkey.
Background: It was our impression that safety outcome trials were getting more frequent, raising ethical issues mainly related to patient autonomy. We and others had also proposed this autonomy would be best served if wording of the informed consents would be in the public domain.
Methods: Initially two observers and an arbiter tabulated the main aims of randomized controlled trials (RCTs) published in 1990-1991 vs.
Low-Waste Technology for High-Precision Connecting Rod Forging Manufacturing.
Materials (Basel)
January 2025
Department of Metal Forming, Welding and Metrology, Wroclaw University of Science and Technology, Lukasiewicza Street 5, 50-370 Wroclaw, Poland.
This study refers to the application of an advanced tool in the form of numerical modelling in order to develop a low-waste hot die forging technology to produce a connecting rod forging. The technology aims at ensuring a limited amount of the charge material is necessary to produce one forging, as well as minimizing forging forces, and thus the electric energy consumption. The study includes a verification of the current production technology, which constituted the basis for the construction and development of a numerical model.
View Article and Find Full Text PDFGiant pit craters on the modern seafloor above magma-induced hydrothermal vent complexes of Scotia Sea, offshore Antarctica.
Sci Rep
January 2025
Department of Geology, School of Natural Sciences, Trinity College Dublin, Dublin, Ireland.
Massive injection of C depleted carbon to the ocean and atmosphere coincided with major environmental upheaval multiple times in the geological record. For several events, the source of carbon has been attributed to explosive venting of gas produced when magmatic sills intruded organic-rich sediment. The concept mostly derives from studies of a few ancient sedimentary basins with numerous hydrothermal vent complexes (HTVCs) where craters appear to have formed across large areas of the seafloor at the same time, but good examples remain rare in strata younger than the Early Eocene.
View Article and Find Full Text PDFPharmacist accessibility for non-native Japanese speakers: A cross-sectional study in Japan.
Can Pharm J (Ott)
January 2025
Department of Social & Community Pharmacy, School of Pharmaceutical Sciences, Wakayama Medical University, Wakayama, Japan.
Background: Pharmacists, being one of the more readily accessible primary health care professionals, must ensure accessibility. With growing internationalization, those in Japanese community pharmacies increasingly interact with non-Japanese speakers. This study aimed to understand how Japanese pharmacies can fulfill accessibility needs by accounting for patients' native language and culture.
View Article and Find Full Text PDFTransfer accuracy of partially enclosed single hard vacuum-formed trays with 3D-printed models for lingual bracket indirect bonding: A prospective in-vivo study.
PLoS One
January 2025
Faculty of Dentistry, Van Lang University, Ho Chi Minh, Vietnam.
Objective: This study aims to evaluate the clinical transfer accuracy of partially enclosed single hard vacuum-formed trays based on three-dimensional (3D) printed models for lingual bracket indirect bonding.
Materials And Methods: Thirty-two consecutive patients receiving lingual orthodontic treatment were enrolled. Digital models with ideal bracket positions were 3D-printed, followed by fabrication of partially enclosed single hard vacuum-formed trays.
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