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Association of multidimensional schizotypy with cognitive-behavioral disorganization in daily life: An experience sampling methodology study.
Personal Disord
January 2025
Department of Psychology, University of Illinois at Urbana-Champaign.
Schizotypy is a multidimensional construct that is composed of positive, negative, and disorganized dimensions. Historically, disorganized schizotypy, which involves disruptions in thoughts, speech, behavior, and affect, has been relatively understudied and less clearly operationalized than the other dimensions. The present study employed experience sampling methodology to examine the associations of positive, negative, and disorganized schizotypy, as measured by the Multidimensional Schizotypy Scale, with daily life experiences.
View Article and Find Full Text PDFA Statistically-Robust Model of the Axomyelin Unit under Normal Physiologic Conditions with Application to Disease States.
ASN Neuro
January 2025
Department of Anesthesiology, University of Illinois at Chicago, Chicago, Illinois, USA.
Despite tremendous progress in characterizing the myriad cellular structures in the nervous system, a full appreciation of the interdependent and intricate interactions between these structures is as yet unfulfilled. Indeed, few more so than the interaction between the myelin internode and its ensheathed axon. More than a half-century after the ultrastructural characterization of this axomyelin unit, we lack a reliable understanding of the physiological properties, the significance and consequence of pathobiological processes, and the means to gauge success or failure of interventions designed to mitigate disease.
View Article and Find Full Text PDFAnesthesia for the Pregnant Patient Undergoing Intracranial Procedures.
J Neurosurg Anesthesiol
January 2025
Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia.
This focused review explores the current literature on anesthetic care of pregnant patients requiring intracranial intervention. Neuropathology in pregnancy is rare, and existing evidence for management remains limited by the ethical complexities surrounding maternal and fetal research-related risks; pregnant women are typically excluded from randomized controlled trials. Physiological changes during pregnancy, combined with additional fetal considerations, alter pharmacodynamics and complicate the safety profile of maternal interventions.
View Article and Find Full Text PDFReimagining Physician Assistant Education: Championing Cognitive Diversity to Promote Inclusivity, Neurodiversity Awareness, and a Sense of Belonging.
J Physician Assist Educ
January 2025
Tonya C. George, PhD, MSHS, MSPH, PA-C, DFAAP, is a assistant professor, Doctor of Medical Science Program, School of Health and Rehabilitation Sciences, University of Pittsburgh, Pittsburgh, Philadelphia.
Neurodiversity, encompassing conditions such as autism spectrum disorder, attention-deficit/hyperactivity disorder, and dyslexia, represents a significant and often under-recognized segment of the population, including within science, technology, engineering, mathematics, and medicine fields like medicine. Neurodiverse individuals possess unique skills, including enhanced creativity, analytical thinking, and meticulous attention to detail, which are valuable in health care professions. However, failure to recognize and support these individuals can result in missed opportunities, social isolation, and mental health challenges.
View Article and Find Full Text PDFReasons Why Patients Do Not Return to Sport Post ACLReconstruction: A Cross-Sectional Study.
J Multidiscip Healthc
January 2025
School of Medicine, The University of Jordan, Amman, 11942, Jordan.
Background: Patients who incur an anterior cruciate ligament (ACL) injury and undergo ACL reconstruction (ACLR) have the intention of returning to sports at their pre-injury level; however, many do not return to the pre-injury level. This study aims to investigate the common factors that hinder patients from resuming sports activities following ACLR and to assess how these barriers impact their ability to return to sports. We hypothesized that patients' psychological factors, including fear of reinjury, would significantly influence their decision to return to sport after ACL reconstruction.
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