Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3181/00379727-131-33918 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Free-Breathing Respiratory Triggered High-Pitch Lung CT: Insights From Phantom and Patient Scans.
Invest Radiol
January 2025
From the Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (A. Schwarz, A. Simon, A.M.); Siemens Healthineers AG, Forchheim, Germany (A. Schwarz, C.H., J.D., A. Simon); Institute for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany (F.K.W., S.G., M.S.); and Institut for Radiology, Pediatric and Neuroradiology, Helios Hospital, Schwerin, Germany (H.-J.R.).
Objective: Respiratory motion can affect image quality and thus affect the diagnostic accuracy of CT images by masking or mimicking relevant lung pathologies. CT examinations are often performed during deep inspiration and breath-hold to achieve optimal image quality. However, this can be challenging for certain patient groups, such as children, the elderly, or sedated patients.
View Article and Find Full Text PDFInforming ICU Digital Twins: Dynamic Assessment of Cardiorespiratory Failure Trajectories in Patients with Sepsis.
Shock
January 2025
Department of Industrial and Systems Engineering, University of Florida, P.O. Box 116595, Gainesville, FL, 32611, USA.
Understanding clinical trajectories of sepsis patients is crucial for prognostication, resource planning, and to inform digital twin models of critical illness. This study aims to identify common clinical trajectories based on dynamic assessment of cardiorespiratory support using a validated electronic health record data that covers retrospective cohort of 19,177 patients with sepsis admitted to ICUs of Mayo Clinic Hospitals over eight-year period. Patient trajectories were modeled from ICU admission up to 14 days using an unsupervised machine learning two-stage clustering method based on cardiorespiratory support in ICU and hospital discharge status.
View Article and Find Full Text PDFLysosomal dysfunction and inflammatory sterol metabolism in pulmonary arterial hypertension.
Science
January 2025
Center for Pulmonary Vascular Biology and Medicine, Pittsburgh, Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, USA.
Vascular inflammation regulates endothelial pathophenotypes, particularly in pulmonary arterial hypertension (PAH). Dysregulated lysosomal activity and cholesterol metabolism activate pathogenic inflammation, but their relevance to PAH is unclear. Nuclear receptor coactivator 7 () deficiency in endothelium produced an oxysterol and bile acid signature through lysosomal dysregulation, promoting endothelial pathophenotypes.
View Article and Find Full Text PDFLong-term smoking contributes to aging frailty and inflammatory response.
Biomol Biomed
January 2025
China Tobacco Sichuan Industrial Co., Ltd., Chengdu, China; Harmful Components and Tar Reduction in Cigarette Key Laboratory of Sichuan Province, Chengdu, China; Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
In recent years, the health challenges linked to frailty in the elderly, particularly those worsened by cigarette smoke, have become more pronounced. However, quantitative studies examining the impact of smoking dosage on frailty in this population remain limited. To address this gap, we developed a model using smoke-exposed elderly mice.
View Article and Find Full Text PDFEffect of blindfolding the lead resuscitator on frequency of closed-loop communication during veterinary cardio-pulmonary resuscitation training: a randomized, controlled pilot study.
Front Vet Sci
January 2025
Dick White Referrals, part of Linnaeus Veterinary Limited, Cambridgeshire, United Kingdom.
Objective: To evaluate the effect of blindfolding the lead resuscitator during veterinary cardiopulmonary resuscitation (CPR) simulation training sessions on frequency of completed closed-loop communication statements (CLC).
Design: Ten groups of staff volunteers were recruited for a prospective, randomized, blinded, observational pilot study over a 6-month period. Additionally, two associated online questionnaires were completed by participants.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!