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Aim: To study efficacy of treating patients with acute coronary syndrome (ACS) without ST segment elevation (STSE) with platelet dysaggregation drugs (aspirin, cardiomagnil, clopidogrel).
Material And Methods: 78 ACS without STSE were randomized into five groups: group 1 patients (n = 17) received no dysaggregants; patients of group 2 (n = 26) received aspirin in the dose 250 mg on the day of admission and then 125 mg/day; group 3 was given cardiomagnil (150 mg on the day of admission and then 75 mg/day, n = 17); group 4--clopidogrel 75 mg/day (n = 7); group 5--combination of clopidogrel 75 mg/day with cardiomagnil 75 mg/day (n = 11). All the patients were administered fraxiparin 86 IU/kg sc each 12 hours for 5-8 days.
[Role of red blood cell changes in chronic occlusion of low limb arteries].
Klin Med (Mosk)
August 2000
To study morphofunctional status of red blood cells, peripheral blood was investigated in 49 patients with chronic occlusions of low limb arteries (COLLA) and 23 healthy donors matched by gender and age. Circulation in the limbs was assessed by infrared thermography. Photometry provided data on microrheological properties of blood by reversible red cell aggregation.
View Article and Find Full Text PDF[Low doses of acetylsalicylic acid effectively inhibits thrombocyte aggregation after ischemic stroke].
Orv Hetil
March 1996
Debreceni Orvostudományi Egyetem Ideg- és Elmegyógyászati Klinika.
Platelet aggregation was examined in 43 patients after ischemic stroke and in 16 healthy subjects using multiparametric aggregation index (MAI). The value of MAI was significantly higher in stroke patients (3.15 in patients and 0.
View Article and Find Full Text PDF[Platelet aggregation in diabetes mellitus at various stages of development of retinopathy].
Probl Endokrinol (Mosk)
October 1979
ADP-induced platelet aggregation was investigated in patients with diabetes mellitus at various stages of the development of retinopathy. Two parameters were used to evaluate the aggregation activity of platelets: the degree of aggregation and the dysaggregation percentage. There was revealed a direct correlation between the platelet hyperaggregation and the degree of diabetic retinopathy.
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