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Prognostic value of coronary artery calcium scoring in patients with non-small cell lung cancer using initial staging computed tomography.
BMC Med Imaging
December 2024
Department of Radiology, Cardiothoracic Imaging, University of Utah, 30 N 1900 E #1A71, Salt Lake City, Utah, 84132, USA.
Background: Lung cancer is a leading cause of cancer-related mortality worldwide, with non-small cell lung cancer (NSCLC) comprising 85% of cases. Due to the lack of early clinical signs, metastasis often occurs before diagnosis, impacting treatment and prognosis. Cardiovascular disease (CVD) is a common comorbidity in lung cancer patients, with shared risk factors exacerbating outcomes.
View Article and Find Full Text PDFCitric acid is more effective than sodium thiosulfate in chelating calcium in a dissolution model of calcinosis.
Sci Rep
December 2024
Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester and Northern Care Alliance NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, M13 9PT, UK.
Calcinosis cutis affects 20-40% of patients with systemic sclerosis. This study tests the hypothesis that calcium-chelating polycarboxylic acids can induce calcium dissolution without skin toxicity or irritancy. We compared citric acid (CA) and ethylenediaminetetraacetic acid (EDTA) to sodium thiosulfate (STS) for their ability to chelate calcium in vitro using a pharmaceutical dissolution model of calcinosis (hydroxyapatite (HAp) tablet), prior to evaluation of toxicity and irritancy in 2D in vitro skin models.
View Article and Find Full Text PDFIdiopathic scrotal calcinosis: Case report and literature review.
Int J Surg Case Rep
December 2024
Department of Outpatient, Zaozhuang Municipal Hospital, 41th, Zaozhuang, China. Electronic address:
Introduction: This case report discusses the clinical manifestations, diagnosis and treatment of idiopathic scrotal calcinosis, and reviews the literature of similar cases, providing important reference for the diagnosis and treatment of this rare disease.
Case Presentation: Idiopathic scrotal calcinosis is a rare condition characterized by calcium deposition in the skin of the scrotum. We present a case of a 67-year-old male patient with idiopathic scrotal calcinosis, a rare condition characterized by calcium deposition in the skin of the scrotum.
Study on the use of intravascular ultrasound-guided coronary intravascular lithotripsy compared with rotational atherectomy: a single-center, retrospective study.
J Int Med Res
December 2024
Department of Cardiology, General Hospital of Ningxia Medical University, Yinchuan, People's Republic of China.
Objective: This study aimed to compare the efficacy and safety of intravascular ultrasound (IVUS)-guided coronary intravascular lithotripsy and rotational atherectomy in treating severe coronary artery calcification.
Methods: A retrospective analysis of 60 patients who underwent percutaneous coronary intervention at the General Hospital of Ningxia Medical University from October 2022 to August 2023 was conducted. The patients were divided into two groups: 30 received IVUS-guided coronary intravascular lithotripsy and 30 underwent IVUS-guided rotational atherectomy.
The relationship between radiographic disc calcification score and FGF4L2 genotype in dachshunds.
J Vet Intern Med
December 2024
Animal Sciences, Oregon State University, Corvallis, Oregon, USA.
Background: The relationship between radiographic disc calcification score and FGF4L2 genotype has been reported in only a small number of dachshunds.
Hypothesis: A genotype with either 0 or 1 FGF4L2 copy will be associated with a lower number of calcified discs (lower K-n) compared with a genotype with 2 FGF4L2 copies.
Animals: Dachshunds registered with the Norwegian or Finnish Kennel Clubs for which both K-n and FGF4L2 genotype are known (n = 407).
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