An anomalous Ullman reaction with 2-chloronicotinic acid is described. The resulting product 2',6'-di-methyl-anilide of 2-pyridone-3-carboxylic acid (isonixine) presents very interesting pharmacological properties as a potential analgesic-anti-inflammatory agent. Chemical and pharmacological data are given.

Download full-text PDF

Source

Publication Analysis

Top Keywords

anomalous ullman
8
2-chloronicotinic acid
8
pharmacological properties
8
ullman additions
4
additions 2-chloronicotinic
4
acid pharmacological
4
properties isonixine
4
isonixine anti-inflammatory
4
anti-inflammatory drug
4
drug anomalous
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!