The histological reactions to the implantation of allogenetic and xenogenetic lyophilized and gamma-sterilized material into the middle ear of rabbits and men is described. In contrary to the behaviour of allogenetic material the xenogenetic shows a clear minor tendency of revitalisation. The reason is the antigen-antibody-reaction which takes place at the capillary network of the donor and leads to a hylinosis with following obliteration of the vascular rete. Therefore the angiogenetic osteogenesis cannot develop. The clinical usuability of such material is discussed.
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http://dx.doi.org/10.1007/BF00453888 | DOI Listing |
Mater Sci Eng C Mater Biol Appl
November 2019
Univ. Bordeaux, INSERM, Laboratory BioTis, UMR 1026, F-33076 Bordeaux, France; CHU Bordeaux, Department of Oral Surgery, F-33076 Bordeaux, France.
PLoS One
March 2020
Division of Veterinary Surgery, Department of Clinic and Animal Surgery, College of Agricultural Sciences and Veterinary Medicine, São Paulo State University "Julio de Mesquita Filho", Jaboticabal Campus, São Paulo, Brazil.
The objective of this study was to evaluate the use of a lyophilized and gamma-sterilized allogeneic freeze-dried bone wedge as a spacer for advancement of a modified tibial tuberosity (mTTA) in 16 knees that were clinically diagnosed with cranial cruciate ligament disease. Patients underwent radiography before the surgical procedure as well as immediately after surgery and at 30, 60, 90 and 120 days post-surgery, and their locomotion was evaluated at the same time points except for the immediate postoperative period. The surgical wounds were evaluated for signs of infection and rejection of the bone implant.
View Article and Find Full Text PDFPlatelets
January 2015
Biorigen Srl , Genoa , Italy .
Serum of animal origin and in particular fetal bovine serum is the most commonly utilized cell culture medium additive for in vitro cell growth and differentiation. However, several major concerns have been raised by the scientific community regarding the use of animal sera for human cell-based culture applications. Among the possible alternatives to the animal serum, platelet-derived compounds have been proposed since more than 10 years.
View Article and Find Full Text PDFThe histological reactions to the implantation of allogenetic and xenogenetic lyophilized and gamma-sterilized material into the middle ear of rabbits and men is described. In contrary to the behaviour of allogenetic material the xenogenetic shows a clear minor tendency of revitalisation. The reason is the antigen-antibody-reaction which takes place at the capillary network of the donor and leads to a hylinosis with following obliteration of the vascular rete.
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