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Full Spectral Overlap to Enhanced Fluorescence Quenching Ability by Using Covalent Organic Frameworks as a Springboard of Quencher for the Turn-on Fluorescence Immunoassay.
Anal Chem
January 2025
College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi 712100, China.
According to the fluorescence internal filtering effect (IFE), the more the absorption spectrum of the quencher overlaps with the excitation and emission spectra of the fluorescent substance, the better the quenching effect and, correspondingly, the more significant and sensitive the contrast becomes when the fluorescence is turned on. Thus, in the competitive fluorescence-quenching lateral flow immunoassays (FQ-LFIAs), the fluorescence quencher with an outstanding optical property is of great importance. Herein, gold nanoparticles (AuNPs) and polydopamine (PDA) coengineered covalent organic frameworks (COF/Au@PDA) were synthesized as a fluorescence quencher to increase spectral overlap.
View Article and Find Full Text PDFCarbazolyl-Decorated Metal-Organic Framework with a High Fluorescent Quantum Yield for Detection and Photocatalytic Degradation of Organic Contaminants.
Inorg Chem
November 2024
State Key Laboratory of Supramolecular Structure and Materials, Institute of Theoretical Chemistry, College of Chemistry, Jilin University, Changchun 130021, P.R. China.
A carbazolyl-based fluorescent metal-organic framework with deep-blue light emission and a high quantum yield (88%) has been screened out by changing the ratio of mixed ligands, named Cz-MOF-2, which was constructed by ZrO(OH) clusters, 3-(9-ethyl-9-carbazol-3-yl)-4-methylthieno[2,3-]thiophene-2,5-dicarboxylate (HECMTDC) and 3,4-dimethyl-dihydrothieno[2,3-]thiophene-2,5-dicarboxylate (HDMTDC). Cz-MOF-2 has excellent sensitivity in fluorescent sensing of 2,6-dichloro-4-nitroaniline (DCN), nitrofurazone (NZF), and nitrofurantoin (NFT) with detection limits of 3.37 × 10, 1.
View Article and Find Full Text PDFMedicated Foley Catheters Do Not Prevent Catheter-Associated Urinary Tract Infection: A Systematic Review of Randomized Controlled Trials.
Cureus
August 2024
Department of Pharmacology, Sir Seewosagur Ramgoolam Medical College, Belle Rive, MUS.
Infections of the urinary tract are among some of the most common infections treated in clinical practice. Numerous risk factors play an intrinsic role in the development of such infections, namely: age, sexual intercourse, prolonged use of feminine hygiene products, instrumentation, pregnancy, sexually transmitted infections, obstructive uropathy such as prostatic enlargement or urethral strictures, compromised immunity, and constipation. A major cause of urinary tract infections (UTIs) in hospitalized patients is catheter-associated urinary tract infections (CAUTIs).
View Article and Find Full Text PDFResearch progress on metabolites of nitrofurazone in aquatic products.
Heliyon
April 2024
(East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai, China.
The carcinogenic and teratogenic risks of nitrofurazone (NFZ) led to its restriction in aquatic products. Semicarbazide (SEM), one of its metabolites, is a primary focus of modern monitoring techniques. However, the SEM residue in aquatic products is believed to be formed through endogenous mechanisms, especially for aquatic crustaceans.
View Article and Find Full Text PDFAn approach to evaluating seasonal responses to acute toxicity of antibiotic nitrofurazone on periphytic ciliated protist communities in marine environments.
Eur J Protistol
June 2024
Laboratory of Microbial Ecology, Ocean University of China, Qingdao 266003, China. Electronic address:
Periphytic protists including ciliates are the primary components of microbial communities in which they play a vital role in the progression of food webs by moving resources from lower to higher trophic levels. However, the toxic effects of veterinary antibiotics on periphytic protists across four seasons are minimally understood. Therefore, in this study, a 1-year survey was conducted with the antibiotic nitrofurazone (NFZ) applied at concentrations of 0.
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