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Naturally occurring variation in a cytochrome P450 modifies thiabendazole responses independently of beta-tubulin.
PLoS Pathog
January 2025
Department of Biology, Johns Hopkins University, Baltimore, Maryland, United States of America.
Widespread anthelmintic resistance has complicated the management of parasitic nematodes. Resistance to the benzimidazole (BZ) drug class is nearly ubiquitous in many species and is associated with mutations in beta-tubulin genes. However, mutations in beta-tubulin alone do not fully explain all BZ resistance.
View Article and Find Full Text PDFChickpea displays a temporal growth response to Mesorhizobium strains under well-watered and drought conditions.
Physiol Plant
January 2025
School of Agriculture, Food and Wine, The University of Adelaide, Urrbrae, SA, Australia.
The relative performance of rhizobial strains could depend on their resource allocation, environmental conditions, and host genotype. Here, we used a high-throughput shoot phenotyping to investigate the effects of Mesorhizobium strain on the growth dynamics, nodulation and bacteroid traits with four chickpea (Cicer arietinum) varieties grown under different water regimes in an experiment including four nitrogen sources (two Mesorhizobium strains, and two uninoculated controls: nitrogen fertilised and unfertilised) under well-watered and drought conditions. We asked three questions.
View Article and Find Full Text PDFCompàreGenome: a command-line tool for genomic diversity estimation in prokaryotes and eukaryotes.
BMC Bioinformatics
January 2025
Technology Park of Sardinia, Bioecopest Srl, SP 55 Km 8.400, Tramariglio, Alghero, SS, Italy.
Background: The increasing availability of sequenced genomes has enabled comparative analyses of various organisms. Numerous tools and online platforms have been developed for this purpose, facilitating the identification of unique features within selected organisms. However, choosing the most appropriate tools can be unclear during the initial stages of analysis, often requiring multiple attempts to match the specific characteristics of the data.
View Article and Find Full Text PDFNumerical analysis of the hydraulic fracture propagation behavior encountering gravel in conglomerate reservoirs.
Sci Rep
January 2025
State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation, Southwest Petroleum University, Chengdu, 610500, China.
Hydraulic fracturing, which forms complex fracture networks, is a common technique for efficiently exploiting low-permeability conglomerate reservoirs. However, the presence of gravel makes conglomerate highly heterogeneous, endowing the deformation, failure, and internal micro-scale fracture expansion mechanisms with uniqueness. The mechanism of fracture expansion when encountering gravel in conglomerate reservoirs remains unclear, challenging the design and effective implementation of hydraulic fracturing.
View Article and Find Full Text PDFX-ray Nanoimaging of a Heterogeneous Structural Phase Transition in VO.
Nano Lett
January 2025
Department of Materials Science and Engineering, Cornell University, Ithaca, New York 14853, United States.
Controlling the Mott transition through strain engineering is crucial for advancing the development of memristive and neuromorphic computing devices. Yet, Mott insulators are heterogeneous due to intrinsic phase boundaries and extrinsic defects, posing significant challenges to fully understanding the impact of microscopic distortions on the local Mott transition. Here, using a synchrotron-based scanning X-ray nanoprobe, we studied the real-space structural heterogeneity during the structural phase transition in a VO thin film.
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