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Regulatory effects of HBUAS52074 on depression-like behavior induced by chronic social defeat stress in mice: modulation of the gut microbiota.
Food Funct
January 2025
Hubei Provincial Engineering and Technology Research Center for Food Ingredients, Hubei University of Arts and Science, Xiangyang, Hubei, PR China.
The gut microbiome has emerged as a growing focus of research and public health interest, leading to the frequent exploration of probiotic dietary supplements as potential treatments for various disorders, such as anxiety and depression. In the present report, changes in inflammation and microbiome composition were assessed in model mice exhibiting depressive-like behaviors that were exposed to the probiotic HBUAS52074. It was found that HBUAS52074 alleviated the severity of depressive-like behaviors while increasing serum 5-HT concentrations.
View Article and Find Full Text PDFEvaluation of the clinical efficacy of CCFM6432 in alleviating depression.
Microbiome Res Rep
September 2024
State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, Jiangsu, China.
Accumulating evidence highlights the crucial role of the "gut-brain axis" and emphasizes the potential of dietary interventions to improve brain health through this pathway. This study assesses the effects of the probiotic CCFM6432 on mood, sleep, and gastrointestinal function in patients with depressive disorder. This clinical trial is a randomized, placebo-controlled study (Registration: ChiCTR2300071025).
View Article and Find Full Text PDFEffects of Powder on the Growth Performance, Immune Organ Weights, Cecal Microbiology, Serum Immunoglobulins, and Tibia Minerals of Broiler Chickens.
Vet Sci
December 2024
Department of Monogastric Animals, Institute of Animal Science, Central Highway km 47 ½, San José de las Lajas C.P. 32700, Mayabeque, Cuba.
A total of 640 one-day-old Cobb 500 MV × Cobb 500 FF mixed broilers were randomly assigned to one of four experimental treatments with four replicates per treatment and 40 birds per replicate for 32 days. The treatments consisted of a basal diet (control group), basal diet + 0.02% zinc bacitracin (AGP group), basal diet + 0.
View Article and Find Full Text PDFChemical-functional characterization of and and dietary supplementation in post-weaning pigs.
Front Vet Sci
December 2024
Department of Veterinary Medicine and Animal Science (DIVAS), University of Milan, Lodi, Italy.
Introduction: As the livestock industry grapples with the need for sustainable land, maintaining production systems, and reducing antimicrobial resistance, the application of functional nutrition emerges as a potential solution.
Aim: In line with the One Health principles, this study aims to evaluate functional properties of and and assess the effects of their dietary supplementation on piglets' health.
Materials And Methods: A chemical-functional characterization was conducted before and after digestion.
Case Report: A novel hemizygous missense variant in a Vietnamese boy with pyruvate dehydrogenase E1-alpha deficiency.
Front Pediatr
December 2024
Institute of Genome Research, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam.
A pyruvate dehydrogenase complex deficiency causes a reduction in adenosine triphosphate production and energy insufficiency, leading to neurological disorders. An abnormal E1-alpha protein originating from the gene with pathogenic variants is unable to communicate with E1-beta for the formation of the E1 enzyme, decreasing pyruvate dehydrogenase complex activity. In this study, we report a Vietnamese boy with lethargy, severe metabolic acidosis, increased serum lactate, hyperalaninemia, lactic acidosis, and globus pallidus lesions.
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