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A Newly Developed Chest Drainage Unit with an Integrated CO2 Detector.
Surg Technol Int
November 2020
Department of Cardiothoracic Surgery, Odense University Hospital, Odense, Denmark.
Purpose: Postoperative air leakage does not always originate from parenchymal defects. In some cases, it may arise from defects in the chest drainage unit itself or connections, or from reverse airflow in water seals. The aim of the present study was to test a new chest drainage unit in the clinic, where an integrated CO2-sensitive colour indicator helps to distinguish false air leakage from true air leakage.
View Article and Find Full Text PDFThe oceans absorb ~25% of the annual anthropogenic CO2 emissions. This causes a shift in the marine carbonate chemistry termed ocean acidification (OA). OA is expected to influence metabolic processes in phytoplankton species but it is unclear how the combination of individual physiological changes alters the structure of entire phytoplankton communities.
View Article and Find Full Text PDFAnatomical and functional connections between the locus coeruleus and the nucleus tractus solitarius in neonatal rats.
Neuroscience
June 2016
Dept of Neuroscience, Cell Biology and Physiology, Wright State University, Dayton, OH, USA. Electronic address:
This study was designed to investigate brain connections among chemosensitive areas in newborn rats. Rhodamine beads were injected unilaterally into the locus coeruleus (LC) or into the caudal part of the nucleus tractus solitarius (cNTS) in Sprague-Dawley rat pups (P7-P10). Rhodamine-labeled neurons were patched in brainstem slices to study their electrophysiological responses to hypercapnia and to determine if chemosensitive neurons are communicating between LC and cNTS regions.
View Article and Find Full Text PDFAnalysis of Sensitive CO2 Pathways and Genes Related to Carbon Uptake and Accumulation in Chlamydomonas reinhardtii through Genomic Scale Modeling and Experimental Validation.
Front Plant Sci
February 2016
Grupo de Diseño de Productos y Procesos, Department of Chemical Engineering, Universidad de los Andes Bogotá, Colombia.
The development of microalgae sustainable applications needs better understanding of microalgae biology. Moreover, how cells coordinate their metabolism toward biomass accumulation is not fully understood. In this present study, flux balance analysis (FBA) was performed to identify sensitive metabolic pathways of Chlamydomonas reinhardtii under varied CO2 inputs.
View Article and Find Full Text PDFHypercapnia modulates cAMP signalling and cystic fibrosis transmembrane conductance regulator-dependent anion and fluid secretion in airway epithelia.
J Physiol
March 2016
Institute for Cell & Molecular Biosciences, The Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.
Hypercapnia is clinically defined as an arterial blood partial pressure of CO2 of above 40 mmHg and is a feature of chronic lung disease. In previous studies we have demonstrated that hypercapnia modulates agonist-stimulated cAMP levels through effects on transmembrane adenylyl cyclase activity. In the airways, cAMP is known to regulate cystic fibrosis transmembrane conductance regulator (CFTR)-mediated anion and fluid secretion, which contributes to airway surface liquid homeostasis.
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