In a retrospective study of neoplasms in Equidae pre;ented to the Animal Disease Diagnostic Laboratory, Purdue University, from Jan 1, 1970, to Dec 31, 1974, data were compiled on numbers and anatomic sites of neoplasms as well as on age, sex, and breed of subjects from which the neoplasms were taken. During this 5-year period, 21 neoplasms were diagnosed from 687 equine necropsies (3.1%) and 215 from 635 biopsies (33.9%), totaling 236 neoplasms from 1,322 cases (17.9%). The most common neoplasms were sarcoids (43.6%) and squamous cell carcinomas (24.6%). Papillomas (5.5%), nerve sheath tumors (4.2%), melanomas (3.8%), lipomas (3.0%), granulosa cell tumors (2.5%), fibromas (2.1%), cholesteatomas (1.3%), and lymphosarcomas (1.3%) were less common.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Phosphorylation of SNW1 protein associated with equine melanocytic neoplasm identified in serum and feces.
Sci Rep
December 2024
Department of Clinical Science and Public Health, Faculty of Veterinary Science, Mahidol University, Salaya, Puttamonthon, Nakhon Pathom, 73170, Thailand.
Equine melanocytic neoplasm (EMN) represents a form of skin tumor observed predominantly in grey horses aged over 15 years. Despite its prevalence, current therapeutic and preventive strategies for EMN have been subject to limited investigation. This study endeavors to shed light on potential phosphoproteins present in equine serum and fecal samples, potentially linked to EMN, with a specific focus on functional interactions in EMN pathogenesis.
View Article and Find Full Text PDF[Retrospective study of the effectiveness of human tyrosinase vaccination in eight horses].
Schweiz Arch Tierheilkd
December 2024
Department für Pferde, Klinik für Pferdechirurgie, Vetsuisse-Fakultät, Universität Zürich.
Dermal melanoma is a common neoplastic disease in horses, which occurs particularly in gray horses. There are various local and systemic therapeutic approaches to treat this skin tumor. Vaccination with human tyrosinase, ONCEPT ® vaccine, is a newer type of systemic melanoma therapy.
View Article and Find Full Text PDFBilateral congenital cystic eye with intraocular tissue differentiation in a horse.
J Vet Med Sci
January 2025
Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University, Hokkaido, Japan.
Congenital cystic eye (CCE) is a rare congenital ocular disease, which has been suggested to be caused by problems with optic vesicle invagination. This is characterized by the formation of intraorbital cystic lesions lined by undifferentiated neuroepithelium. However, cases involving ocular structures with varying degrees of differentiation have also been reported as CCE in humans and animals.
View Article and Find Full Text PDFVascular hamartoma in horse limbs: presentation, diagnosis, and treatment of two case studies.
Vet Res Commun
November 2024
Department of Veterinary Surgery and Animal Reproduction, São Paulo State University - UNESP, Botucatu, São Paulo, Brazil.
Vascular hamartoma is an abnormal development of endothelial tissue that rarely affects horses. Histopathological examination remains the gold standard for definitive diagnosis, yet the presence of abnormal vascular structures must be carefully differentiated from other vascular anomalies and neoplasms. This report describes two cases of vascular proliferation affecting the skin on the lateral side over the left tarsus and the dorsolateral region over the fetlock joint of two fillies.
View Article and Find Full Text PDFOverexpression of the key metabolic protein Carnitine Palmitoyl Transferase 1A (CPT1A) in equine sarcoid.
J Equine Vet Sci
December 2024
Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Via Delpino 80137, Naples, Italy.
The equine sarcoid is the most common skin neoplasia of fibroblastic origin in horses, characterized by an excessive accumulation of extracellular matrix produced by sarcoid fibroblasts under hypoxic condition. Neoplastic cells can adapt to hypoxia by using alternative energy sources, particularly those that arise from fatty acid oxidation (FAO). The Carnitine Palmitoyl Transferase 1A (CPT1A) belongs to Carnitine System (CS) and promotes the entrance of fatty acids into the mitochondria for β-oxidation.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!