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Pharmacokinetics of ochratoxin A in animals.
IARC Sci Publ
August 1992
Laboratoire de Pharmacologie-Toxicologie, Institut National de la Recherche Agronomique, Toulouse, France.
The fate of ochratoxin A has been studied in laboratory rodents and in breeding animals. In rats, orally administered ochratoxin A is readily absorbed, and considerable amounts of the toxin are detected in plasma, where maximal concentrations occur 2-4 h after administration. Pharmacokinetic analysis of curves of plasma level versus time suggests its distribution in two distinct body compartments.
View Article and Find Full Text PDFCardiac muscle proteins of four inbred murine strains were analyzed by one- and two-dimensional electrophoresis. Of those, 27 and 161 protein fractions were characterized in terms of molecular mass and relative electrophoretic mobility. The protein fractions were identified as corresponding to creatine phosphokinase, myoglobin and an albumin-like protein.
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