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Objective: Reverse obliquity intertrochanteric fracture is an unstable type of fracture. Current guidelines recommend intramedullary fixation, but there are still complications such as screw removal, hip varus, nail withdrawal, and nail fracture. The objective of this study was to use finite element analysis to compare the biomechanical properties of the novel proximal femoral bionic nail (PFBN), proximal femoral nail antirotation (PFNA), and combined compression interlocking intramedullary nail (InterTan) in the treatment of reverse obliquity intertrochanteric fractures (AO/OTA 31-A3.

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Background: Extracellular vesicles (EVs) have procoagulative properties. As EVs are known to accumulate in stored blood products, we compared the EV content and coagulation capacity of leukoreduced cold-stored whole blood (CSWB) with current prehospital and in-hospital component therapies to understand the role of EVs in the haemostatic capacity of ageing CSWB.

Materials And Methods: Blood was obtained from 12 O RhD-positive male donors.

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Is single anastomosis duodenoileal bypass (SADI) an effective option for conversional surgery following sleeve gastrectomy? A comprehensive review and revised scope of current literature.

Obes Res Clin Pract

January 2025

Unit for Multidisciplinary Research in Biomedicine (UMIB), School of Medicine and Biomedical Sciences (ICBAS), University of Porto, Porto, Portugal; Department of General Surgery, Unidade Local de Saúde de Entre o Douro e Vouga, Santa Maria da Feira, Portugal; ITR- Laboratory of Integrative and Translocation Research in Population Health, Porto, Portugal. Electronic address:

Background: Conversional surgery following sleeve gastrectomy (SG) is required in about 20 % of patients due to suboptimal outcomes. Single anastomosis duodenoileal bypass (SADI) has emerged as an option for such cases, though long-term outcomes remain unclear. This review analyzed available data on SADI as a conversional or second-stage procedure after SG.

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Revisiting epigenetic regulation in cancer: Evolving trends and translational implications.

Int Rev Cell Mol Biol

January 2025

Molecular Cancer Genetics & Translational Research Lab, Section of Genetics, Department of Zoology, Aligarh Muslim University, Aligarh, India. Electronic address:

Cancer is a leading cause of mortality worldwide. The evolving role of epigenetics and tumor microenvironments of cancer pose significant challenges to the management of cancer. Besides genetics, epigenetic changes play a crucial role in the alteration of cellular machinery, progression, metastasis, epithelial-mesenchymal transition, and chemoresistance.

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In human-computer interaction, gesture recognition based on physiological signals offers advantages such as a more natural and fast interaction mode and less constrained by the environment than visual-based. Surface electromyography-based gesture recognition has significantly progressed. However, since individuals have physical differences, researchers must collect data multiple times from each user to train the deep learning model.

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