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Detection methods for carbapenem-resistant Pseudomonas aeruginosa in surface water and wastewater.
Sci Total Environ
January 2025
National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands; Department of Biotechnology, Technical University Delft, Delft, the Netherlands. Electronic address:
Water systems can act as an important reservoir for Pseudomonas aeruginosa, which can pose public health risks during human contact. Carbapenem resistance is one of the most concerning resistances in P. aeruginosa making it a high-priority pathogen according to the World Health Organization (WHO), due to its ability to cause difficult-to-treat infections.
View Article and Find Full Text PDFComparing carbon agronomic footprint and sequestration in Central American coffee agroforestry systems and assessing trade-offs with economic returns.
Sci Total Environ
January 2025
CATIE, Centro Agronómico Tropical de Investigación y Enseñanza, Turrialba 30501, Costa Rica.
Agricultural systems are both emitters of greenhouse gases and have the potential to sequester carbon, especially agroforestry systems. Coffee agroforestry systems offer a wide range of intensities of use of agricultural inputs and densities and management of shade trees. We assessed the agronomic carbon footprint (up to farm gate) and modelled the carbon sequestration of a range of coffee agroforestry systems across 180 farms in Costa Rica and Guatemala.
View Article and Find Full Text PDFImplications of plastic ingestion on the growth and fledging success of shearwaters.
Sci Total Environ
January 2025
Institute for Marine and Antarctic Studies, University of Tasmania, Hobart, Australia; CSIRO Environment, Hobart, Australia.
Ingestion of plastic can have negative health consequences for wildlife. However, our understanding of the physiological impacts of plastics is limited, often relying on opportunistic sampling. We partnered with Tasmanian Aboriginal seabird harvesters, wildlife rescue clinics, and parks managers, to collect >400 fledgling yula/short-tailed and flesh-footed shearwaters across a spectrum of body conditions.
View Article and Find Full Text PDFEvaluation of RMplex system for differentiating father-son pairs using Y-STRs in a Korean population.
Forensic Sci Int Genet
January 2025
Forensic DNA Division, National Forensic Service, Wonju, South Korea. Electronic address:
Y-chromosomal short tandem repeats (Y-STRs) at rapidly mutating (RM) loci have been suggested as tools for differentiating paternally related males. RMplex is a recently developed system that incorporates 26 RM loci and four fast-mutating (FM) loci, targeting 44 male-specific loci. Here, we evaluated the RMplex by estimating Y-STR mutation rates and the overall differentiation rates for 542 Korean father-son pairs, as well as the genetic population values for 409 unrelated males.
View Article and Find Full Text PDFIdentification of key gene signatures for predicting chemo-immunotherapy efficacy in extensive-stage small-cell lung cancer using machine learning.
Lung Cancer
January 2025
Internal Medicine III, Wakayama Medical University, Wakayama, Japan.
Objectives: The lack of definitive biomarkers presents a significant challenge for chemo-immunotherapy in extensive-stage small-cell lung cancer (ES-SCLC). We aimed to identify key genes associated with chemo-immunotherapy efficacy in ES-SCLC through comprehensive gene expression analysis using machine learning (ML).
Methods: A prospective multicenter cohort of patients with ES-SCLC who received first-line chemo-immunotherapy was analyzed.
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