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Cervical Adenocarcinoma: A Still Under-investigated Malignancy.
Anticancer Res
January 2023
Division of Gynaecology and Obstetrics, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Background/aim: The aim of the study was to correlate the expression of mismatch repairs proteins (MMR), programmed-death-ligand1 (PDL-1), and estro-progestinic receptors (ER/PgR) in tissue samples from a series of cervical adenocarcinoma (ADC) patients with their clinicopathological features.
Materials And Methods: Thirty-nine ADC specimens were retrospectively retrieved from the Division of Pathology of the University Hospital of Pisa from 2015 to 2021. Histological subtype, grade (G), Silva pattern, presence of lymph vascular space invasion (LVI), and perineural invasion (PNI) were annotated.
Melanoma in female patients: general features and focus on the impact of estro-progestinic pills in prognostic factors.
G Ital Dermatol Venereol
August 2018
University of Magna Graecia, Catanzaro, Italy.
When to operate on ovarian cysts in children?
J Pediatr Endocrinol Metab
September 2012
Division of Pediatric Surgery, Regina Margherita Children's Hospital, Turin, Italy.
Background: Ovarian cysts are rare conditions in the pediatric age group. They are characterized by different clinical presentations and by the need to establish adequate type and timing of treatment in order to prevent complications, such as ovarian necrosis after torsion and infertility. The diagnostic approach should differentiate benign occasional findings, such as follicular cysts, from neoplastic lesions, and functional cysts which can occur either isolated or in the context of McCune-Albright syndrome.
View Article and Find Full Text PDFUse of a progestogen only preparation containing desogestrel in the treatment of recurrent pelvic pain after conservative surgery for endometriosis.
Eur J Obstet Gynecol Reprod Biol
December 2007
Chair of Obstetrics and Gynecology, Department of Pediatric, Obstetrics and Reproductive Medicine, University of Siena, Policlinico Le Scotte, 53100 Siena, Italy.
Objective: To assess the effect of a new progestin progestogen only pill (desogestrel) versus an oral contraceptive in the treatment of recurrent endometriosis.
Study Design: A randomized prospective clinical study. A group of women with endometriosis (n=40) who showed recurrent dysmenorrhea and/or pelvic pain after conservative surgery, and did not desire a pregnancy.
Drospirenone for the treatment of hirsute women with polycystic ovary syndrome: a clinical, endocrinological, metabolic pilot study.
J Clin Endocrinol Metab
June 2004
Department of Obstetrics and Gynecology, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
The aim of this study was to investigate the effects of the new estro-progestinic containing the antimineralcorticoid progestogen drospirenone (DRSP) in women with polycystic ovary syndrome (PCOS). Fifteen hirsute PCOS patients were treated with 30 microg ethinyl estradiol plus 3 mg DRSP for 12 cycles. Ultrasonographic pelvic exams, evaluation of hirsutism scores, and hormonal and lipid profile assays were performed at baseline and after three, six, and 12 cycles of treatment.
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