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Clinico-Epidemiologic Profile and Response to Levocetirizine in Chronic Spontaneous Urticaria: A Retrospective Cohort Study from a Tertiary Care Center in North India.
Indian Dermatol Online J
June 2024
Department of Dermatology, Venereology, and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Article Synopsis
- The study addresses the lack of long-term data on chronic spontaneous urticaria (CSU) in general populations, particularly in the Indian subcontinent.
- It aims to analyze the clinical profile of CSU patients, their comorbidities, and what factors influence their response to levocetirizine, a common antihistamine treatment.
- Findings from 1,104 CSU cases indicate a significant prevalence of thyroid dysfunction, atopy, vitamin D deficiency, and high serum IgE levels, with serum IgE and D-dimer levels being key markers for determining the need for increased levocetirizine dosage.
Comparison of Congenital Rubella Syndrome Cases at a Philippine Tertiary Hospital from 2009-2012 to 2019-2022.
Acta Med Philipp
April 2024
Department of Ophthalmology and Visual Sciences, College of Medicine and Philippine General Hospital, University of the Philippines Manila.
Article Synopsis
- The study focused on congenital rubella syndrome (CRS) in the Philippines, analyzing clinico-epidemiologic data from a tertiary hospital over two periods: 2009-2012 and 2019-2022.
- A total of 42 CRS patients were reviewed, with only 33% confirmed serologically, while the most common manifestations included cataracts and hearing loss.
- The findings highlighted challenges in laboratory diagnosis due to high costs and limited availability, with an increase in CRS cases noted in the later period.
Clinico-Epidemiologic Profile of Non-Syndromic Congenital Ichthyosis - A Retrospective Chart Review of 107 Patients.
Indian J Dermatol
April 2024
From the Department of Dermatology, Venereology, and Leprology, Postgraduate Institute of Medical Education and Research, Sector 12, Chandigarh, India.
Background: Congenital ichthyoses are a rare Mendelian group of disorders affecting the integument with a heterogeneous clinical presentation amongst which scaling is a constant feature. There is scanty epidemiologic data regarding the clinical profile and histologic patterns of inherited ichthyosis from resource-poor countries.
Aims And Objectives: The study was aimed at assessing the clinic-epidemiologic characteristics associated with the different forms of non-syndromic congenital ichthyosis.
Objective This study was conducted to determine the prevalence of urinary tract infection in children with severe acute malnutrition (SAM) aged between six months and five years and to identify the causative organisms and their antibiotic sensitivity pattern. Study design This study was an observational cross-sectional study. Setting and participants The study was conducted in the Department of Paediatrics in a tertiary care hospital in India over a period of 18 months.
View Article and Find Full Text PDFKGHeBTA (King George's Medical University Hepatitis B Therapeutic Algorithm): A New Diagnostic and Therapeutic Algorithm and Clinico-epidemiological Spectrum of Hepatitis B.
J Clin Exp Hepatol
March 2023
Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Article Synopsis
- The study aimed to create a unified treatment algorithm for hepatitis B, termed KGHeBTA, in response to the fragmented guidelines and limited regional data.
- A total of 1,508 patient records were analyzed, revealing that 221 had detectable hepatitis B virus DNA, with 21% diagnosed with cirrhosis and 72% being asymptomatic cases discovered incidentally.
- The study found that only about 20% of patients were eligible for antiviral treatment based on the algorithm, while road-side shaving was identified as the most common risk factor for hepatitis B detection.
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