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Bifrontal Craniectomy: A High-Yield Surgical Training Tool.
Cureus
December 2024
Department of Medical Education, Geisinger Commonwealth School of Medicine, Scranton, USA.
Bifrontal decompressive craniectomy (DC), which was once a popular technique for treating midline mass lesions, has seen a notable decline in its therapeutic use within modern neurosurgery. Despite its diminished clinical use, the procedure offers considerable value as an educational tool for surgical training. This study used a Thiel-embalmed cadaver to demonstrate the bifrontal DC procedure, including a Souttar incision, strategic (MacCarty, zygomatic, and apical) keyhole/burr hole placement, superior sagittal sinus suturing, left frontal lobe decortication, and microscopic visualization of the anterior cranial fossa.
View Article and Find Full Text PDFNext-generation pharmaceuticals: the rise of sildenafil citrate ODF for the treatment of men with erectile dysfunction.
Ther Deliv
January 2025
Global Specialty Excellence, Viatris Inc, New York, USA.
Orodispersible film (ODF) is one of the novel formulations that disintegrate rapidly in the mouth without the requisite for water compared to other conventional oral solid dosage formulations. This delivery system serves as a convenient mode of administration, especially in patients who have dysphagia and fluid restriction, being beneficial to pediatric, geriatric, and bedridden patients. A novel sildenafil ODF containing sildenafil citrate is formulated to be used in patients with erectile dysfunction (ED).
View Article and Find Full Text PDFAutomatic Cleaning of Time Series Data in Rural Internet of Things Ecosystems That Use Nomadic Gateways.
Sensors (Basel)
January 2025
Faculty of Electronics, Telecommunications and Informatics, Gdańsk University of Technology, Narutowicza 11/12, 80-233 Gdańsk, Poland.
A serious limitation to the deployment of IoT solutions in rural areas may be the lack of available telecommunications infrastructure enabling the continuous collection of measurement data. A nomadic computing system, using a UAV carrying an on-board gateway, can handle this; it leads, however, to a number of technical challenges. One is the intermittent collection of data from ground sensors governed by weather conditions for the UAV measurement missions.
View Article and Find Full Text PDFHow should we bend the curve of biodiversity loss to build a just and sustainable future?
Philos Trans R Soc Lond B Biol Sci
January 2025
Georgina Mace Centre for the Living Planet, Silwood Park, Ascot SL5 7PY, UK.
Current rates of habitat and biodiversity loss, and the threat they pose to ecological and economic productivity, would be considered a global emergency even if they were not occurring during a period of rapid anthropogenic climate change. Diversity at all levels of biological organization, both within and among species, and across genomes and communities, is critical for the resilience of the world's ecosystems in the face of such change. However, it remains an urgent scientific challenge to understand how biodiversity underpins these ecological outputs, how patterns of biodiversity are being affected by current threats, and how and where such biodiversity contributes most directly to human economies, well-being and social justice.
View Article and Find Full Text PDFExploring the significance of emerging blue food processing technologies for sustainable development.
Food Res Int
January 2025
Research and Development Cell, Biotechnology Department, Manav Rachna International Institute of Research and Studies (Deemed to Be University), Faridabad 121004, Haryana, India. Electronic address:
Blue food processing applies to the production and processing of fish, algae, and other aquatic organisms for human consumption. As the global population grows and consumer demand for protein-rich foods increases, there is increased interest in exploring a wide range of innovative approaches for processing blue foods in ways that improve the efficiency, sustainability, and nutritional quality of these products and reduce the environmental impact of their production. Existing approaches to process blue foods including fishing and aquaculture for production and manual processing at landing are not sufficiently scalable, efficient, or environmentally sustainable for today's global needs.
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